{"id":"W4252580647","doi":"10.1002/ange.201408641","title":"A Bio‐Inspired Total Synthesis of Tetrahydrofuran Lignans","year":2015,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Plant-derived Lignans Synthesis and Bioactivity","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; McGill University","keywords":"Lignan; Pinoresinol; Total synthesis; Oxidative coupling of methane; Chemistry; Biomimetic synthesis; Ferulic acid; Phenols; Tetrahydrofuran; Stereochemistry; Propenyl; Enantioselective synthesis; Combinatorial chemistry; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000224215,0.0001997331,0.000274832,0.00004444322,0.00003898969,0.00001444836,0.0002031612,0.0002039273,0.00001859042],"category_scores_gemma":[0.0001969168,0.0001714581,0.0001567716,0.0001095469,0.0001234791,0.000007297302,0.00008574375,0.00006281535,0.00001216395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001885292,"about_ca_system_score_gemma":0.0001094948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007231435,"about_ca_topic_score_gemma":0.00002647955,"domain_scores_codex":[0.9989372,0.00003865557,0.0002252648,0.0003337528,0.0001894272,0.0002757329],"domain_scores_gemma":[0.9992149,0.00003410083,0.0001193717,0.0003788507,0.00008384802,0.0001689659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001009926,0.0001332682,0.001728888,0.00002590898,0.00008451514,0.000006133559,0.00005655868,0.000002503085,0.9934266,0.000006791545,0.003011411,0.001416464],"study_design_scores_gemma":[0.0003229684,0.0001372141,0.0008074699,0.00003555383,0.00004568907,0.00003192147,0.0001356774,0.000004269829,0.9907023,0.00001886705,0.007528309,0.0002297961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889354,0.0006360454,0.00006154398,0.0001489942,0.00009899405,0.0001118255,0.0001567437,0.00002275978,0.009827738],"genre_scores_gemma":[0.9988267,0.0001048399,0.000337019,0.0000626356,0.0001881778,0.00002324673,0.00006129379,0.00002326261,0.0003727626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009891406,"threshold_uncertainty_score":0.6991857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02015988579348306,"score_gpt":0.2314206651365238,"score_spread":0.2112607793430407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}