{"id":"W4252580647","doi":"10.1002/ange.201408641","title":"A Bio‐Inspired Total Synthesis of Tetrahydrofuran Lignans","year":2015,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Plant-derived Lignans Synthesis and Bioactivity","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; McGill University","keywords":"Lignan; Pinoresinol; Total synthesis; Oxidative coupling of methane; Chemistry; Biomimetic synthesis; Ferulic acid; Phenols; Tetrahydrofuran; Stereochemistry; Propenyl; Enantioselective synthesis; Combinatorial chemistry; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001107099,0.0004134919,0.0002000711,0.0003000019,0.000172793,0.0002465225,0.0002982643,0.0002539014,0.001939063],"category_scores_gemma":[0.00008008144,0.0001332906,0.0002948745,0.0003606086,0.0001878503,0.0003336046,0.0003481889,0.0004747086,0.0006531688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003317065,"about_ca_system_score_gemma":0.0004092554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004728341,"about_ca_topic_score_gemma":0.001148187,"domain_scores_codex":[0.9999253,0.00000961055,0.000004062112,0.00001705936,0.00001588208,0.00002813688],"domain_scores_gemma":[0.9999655,0.000004761863,0.00000808432,0.000006813837,0.000005341758,0.000009415756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003660884,0.0000586442,0.00008223331,0.0002203273,0.00002320163,0.0002205792,0.00007380892,0.001979464,0.9688789,0.005857045,0.0003817723,0.02218745],"study_design_scores_gemma":[0.00002464786,0.0003248977,0.0004764441,0.00001835309,0.00002458365,0.000240105,0.00003106587,0.002343432,0.9730446,0.001547645,0.02190348,0.00002076209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.799707,0.00758567,0.1459252,0.0006033353,0.0003472965,0.000264981,0.001797832,0.0007518794,0.04301675],"genre_scores_gemma":[0.9482107,0.003971331,0.03875558,0.000101514,0.00002144533,0.00009963312,0.0005001581,0.00005380989,0.008285846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001939063,"threshold_uncertainty_score":0.006486773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02015988579348306,"score_gpt":0.2314206651365238,"score_spread":0.2112607793430407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}