{"id":"W4252590442","doi":"10.21203/rs.3.rs-34021/v6","title":"Metadichol®, a Novel Nano Lipid Formulation that Inhibits SARS-COV-2 and a Multitude of Pathological Viruses in vitro","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Vitamin C and Antioxidants Research","field":"Nursing","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"NanoXplore (Canada)","funders":"","keywords":"Virus; Infectivity; Serine protease; Viral envelope; Virology; In vitro; Lipid bilayer; Biology; Chemistry; Protease; TMPRSS2; Proteases; Microbiology; Lipid bilayer fusion; Coronavirus; Coronavirus disease 2019 (COVID-19); Biochemistry; Membrane; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001808063,0.0002711453,0.0001843931,0.0002659091,0.000101314,0.0002090638,0.000186424,0.0002876782,0.002075082],"category_scores_gemma":[0.0001367449,0.00009519235,0.000217464,0.0001207599,0.0001102486,0.0002924092,0.0001807832,0.0003985342,0.0003215987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000135897,"about_ca_system_score_gemma":0.0002199085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003154802,"about_ca_topic_score_gemma":0.0005564985,"domain_scores_codex":[0.9999326,0.00001202156,0.00000554803,0.00001665048,0.00002400566,0.00000913381],"domain_scores_gemma":[0.9999645,0.000007558841,0.000009993174,0.000003926201,0.000006992333,0.000007043344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005799825,0.0001437389,0.0001117155,0.0002209334,0.00001647939,0.00006948041,0.00002454759,0.00008792969,0.9717165,0.0002412703,0.0003186424,0.02646884],"study_design_scores_gemma":[0.0001834802,0.002661147,0.001170073,0.00003366586,0.0000618148,0.0004450419,0.00002713826,0.0005117667,0.9809224,0.0001133781,0.01386037,0.000009608561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9524686,0.01872754,0.01633891,0.0008258983,0.0005578691,0.0003588499,0.0009875334,0.0002467741,0.009488172],"genre_scores_gemma":[0.9663364,0.008221369,0.01572887,0.0003055358,0.000100443,0.0001297466,0.0008127025,0.00004080868,0.008324133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002075082,"threshold_uncertainty_score":0.006941795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2481985748986877,"score_gpt":0.4501609850442121,"score_spread":0.2019624101455244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}