{"id":"W4252594977","doi":"10.1021/ol016581u","title":"Syn−Anti Isomerization of Aldols by Enolization","year":2001,"lang":"en","type":"article","venue":"Organic Letters","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Keto–enol tautomerism; Isomerization; Chemistry; Adduct; Aldol reaction; Imidazole; Stereochemistry; Medicinal chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004284829,0.0007969107,0.0002049182,0.0003495586,0.0002844718,0.0003095908,0.0003609992,0.0001820527,0.004462529],"category_scores_gemma":[0.0002313637,0.0001521341,0.0001596739,0.0002135766,0.0003055807,0.0004671398,0.0003447013,0.0004941529,0.001276348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002440805,"about_ca_system_score_gemma":0.0002837467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004592871,"about_ca_topic_score_gemma":0.0006429674,"domain_scores_codex":[0.9997994,0.00004816673,0.00001167587,0.00003350594,0.00003290498,0.00007430096],"domain_scores_gemma":[0.9998633,0.00002143401,0.00003768192,0.00002158136,0.00002675067,0.00002935303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007656418,0.0001454465,0.0005525503,0.0001948619,0.00003119628,0.0004062709,0.000287694,0.0004178477,0.9793863,0.00501189,0.00073752,0.01206279],"study_design_scores_gemma":[0.00001830304,0.0002835157,0.0003760259,0.000004328151,0.000009800371,0.0003214615,0.00003259797,0.0003001814,0.9933564,0.0001901956,0.005097269,0.000009714317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9522817,0.003209076,0.01862635,0.0003108808,0.000213727,0.0001321594,0.0003805081,0.0004919271,0.02435357],"genre_scores_gemma":[0.9884067,0.001674034,0.002805583,0.00009042594,0.00002946218,0.00002647615,0.0002296712,0.0000467877,0.00669085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004462529,"threshold_uncertainty_score":0.0149287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009603610595018474,"score_gpt":0.2640139504696309,"score_spread":0.2544103398746125,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}