{"id":"W4252870944","doi":"10.3410/f.726282115.793519469","title":"Faculty Opinions recommendation of A Pharmacogenetic 'Restriction-of-Function' Approach Reveals Evidence for Anxiolytic-Like Actions Mediated by α5-Containing GABAA Receptors in Mice.","year":2016,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"GABAA receptor; Anxiolytic; Pharmacogenetics; Function (biology); Receptor; Neuroscience; Pharmacology; Psychology; Medicine; Biology; Genetics; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001328267,0.001665064,0.001586093,0.002603665,0.0005985812,0.001910888,0.002247814,0.002264238,0.05147235],"category_scores_gemma":[0.0105249,0.0004837568,0.002351844,0.003436559,0.0003799274,0.0009573505,0.001312532,0.001525406,0.0331632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001349881,"about_ca_system_score_gemma":0.003165952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02185947,"about_ca_topic_score_gemma":0.0661792,"domain_scores_codex":[0.9989412,0.0001739186,0.0001462254,0.0003282663,0.0002527228,0.0001576006],"domain_scores_gemma":[0.9967701,0.001283068,0.000494862,0.0005522483,0.0005433387,0.000356233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005480304,0.00005109967,0.005130358,0.003036654,0.0002901845,0.00007030761,0.00002471061,0.0004303103,0.0004780049,0.0004817818,0.984095,0.005363486],"study_design_scores_gemma":[0.001991269,0.00007092161,0.01748971,0.001029947,0.0005251674,0.0001658264,0.00007162668,0.0007461308,0.001105567,0.001710019,0.9750366,0.00005734458],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0003285767,0.0001597878,0.00005335018,0.0001233323,0.00003126658,0.00001858305,0.99847,0.0001889328,0.0006261749],"genre_scores_gemma":[0.00139891,0.0001879748,0.0003929109,0.0001457826,0.0000164654,0.0001265777,0.9966515,0.00006284464,0.001017177],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.05147235,"threshold_uncertainty_score":0.1721922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1334564456126296,"score_gpt":0.4311636573080097,"score_spread":0.29770721169538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}