{"id":"W4252925707","doi":"10.1002/ange.201507548","title":"Kinetic Resolution of Azomethine Imines by Brønsted Acid Catalyzed Enantioselective Reduction","year":2015,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Asymmetric Hydrogenation and Catalysis","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; University of Ottawa","keywords":"Enantioselective synthesis; Kinetic resolution; Chemistry; Imine; Brønsted–Lowry acid–base theory; Catalysis; Enantiomer; Azomethine ylide; Combinatorial chemistry; Organic chemistry; Cycloaddition","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000218585,0.0001716576,0.0002705538,0.0001483617,0.0000477888,0.00001448342,0.0001676909,0.0001722737,0.0002131473],"category_scores_gemma":[0.0004818156,0.0001634463,0.0001072051,0.0009484765,0.00009374236,0.0001390779,0.00004606398,0.0001368597,0.00002297894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001597123,"about_ca_system_score_gemma":0.00007132863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002245018,"about_ca_topic_score_gemma":0.000006513179,"domain_scores_codex":[0.9987424,0.00001635152,0.0003406908,0.0003033541,0.0003812795,0.0002159337],"domain_scores_gemma":[0.9988441,0.000029697,0.0003133973,0.0003115888,0.0003564717,0.0001447545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006451551,0.0001093373,0.0001104185,0.00004176866,0.00009184884,0.000001305778,0.0004213262,0.000007816776,0.9850379,0.00001364623,0.01215374,0.001946419],"study_design_scores_gemma":[0.0009786792,0.00001937288,0.00001695853,0.00001899141,0.0001091356,0.00002010543,0.0004342606,0.00006906581,0.990248,0.0000846429,0.007824906,0.0001759351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9629759,0.003492306,0.0005849882,0.0003066427,0.0001240001,0.00009756609,0.0001020363,0.0001597598,0.03215677],"genre_scores_gemma":[0.9952809,0.00008342295,0.0002356502,0.0000171314,0.0001328638,0.00002131994,0.00086781,0.00002297522,0.003337921],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03230498,"threshold_uncertainty_score":0.6665148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02054489982397761,"score_gpt":0.2497295336887619,"score_spread":0.2291846338647843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}