{"id":"W4253228422","doi":"10.1126/stke.2000.62.tw7","title":"Transcription-Independent p53 Apoptosis Requires Caspase-8","year":2000,"lang":"en","type":"article","venue":"Science s STKE","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Apoptosis; FADD; Cell biology; NLRP1; Inhibitor of apoptosis domain; Transcription factor; Caspase 8; Biology; Caspase; Caspase 10; Intrinsic apoptosis; Transcription (linguistics); Caspase 3; Programmed cell death; Molecular biology; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002235233,0.0003306299,0.0002199899,0.0002479815,0.000155488,0.0004883382,0.0002404938,0.0004238413,0.001311762],"category_scores_gemma":[0.0002973835,0.0001631324,0.0003879573,0.0001224585,0.0001797873,0.0004819965,0.0003093855,0.0007654724,0.001082731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004408258,"about_ca_system_score_gemma":0.0002245277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001889568,"about_ca_topic_score_gemma":0.0002022143,"domain_scores_codex":[0.9996941,0.0000343892,0.00003177807,0.00005956877,0.0001113489,0.00006877902],"domain_scores_gemma":[0.999742,0.00002995295,0.0000544238,0.00004631202,0.00008603211,0.00004128744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001505284,0.00006095234,0.0004694265,0.00005772129,0.000005669916,0.0001610653,0.00002619079,0.00005276389,0.9934673,0.0005893144,0.0002699416,0.004689217],"study_design_scores_gemma":[0.0001395265,0.0004796083,0.01077135,0.00002495129,0.00001589932,0.00103484,0.00004165318,0.002038367,0.9733731,0.0006978599,0.01137018,0.00001271269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9643659,0.007926976,0.01605945,0.001104547,0.0002310141,0.0001255264,0.0004677128,0.0004021171,0.00931677],"genre_scores_gemma":[0.9922919,0.001171144,0.001918196,0.0001178162,0.00002912828,0.00003462697,0.000436972,0.00001146264,0.003988842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001311762,"threshold_uncertainty_score":0.004388213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01647296587621284,"score_gpt":0.2694842480107575,"score_spread":0.2530112821345447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}