{"id":"W4253491780","doi":"10.21203/rs.3.rs-34021/v8","title":"Metadichol®, a Novel Nano Lipid Formulation that Inhibits SARS-COV-2 and a Multitude of Pathological Viruses in vitro","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Vitamin C and Antioxidants Research","field":"Nursing","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"NanoXplore (Canada)","funders":"","keywords":"Infectivity; Virus; Serine protease; Viral envelope; Virology; In vitro; Lipid bilayer; TMPRSS2; Lipid bilayer fusion; Chemistry; Biology; Coronavirus; Protease; Microbiology; Biochemistry; Coronavirus disease 2019 (COVID-19); Membrane; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001803508,0.0002676387,0.0001846745,0.0002648437,0.0001004885,0.0002101921,0.0001833594,0.0002861191,0.002074333],"category_scores_gemma":[0.0001369953,0.00009448982,0.0002179705,0.0001200464,0.0001095236,0.0002925854,0.0001820645,0.0003973368,0.000320857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001352861,"about_ca_system_score_gemma":0.0002212841,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003173206,"about_ca_topic_score_gemma":0.0005527976,"domain_scores_codex":[0.9999337,0.00001181267,0.000005345568,0.00001635691,0.00002371976,0.000009015835],"domain_scores_gemma":[0.9999651,0.000007477882,0.000009830578,0.000003859374,0.000006857014,0.00000688305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006020562,0.0001494629,0.0001174871,0.0002288287,0.00001723534,0.00007287895,0.00002580536,0.00009251644,0.9700155,0.0002588195,0.0003397547,0.02807957],"study_design_scores_gemma":[0.0001866543,0.002633117,0.001192014,0.00003437747,0.00006293592,0.0004442542,0.00002768936,0.0005262293,0.9804785,0.0001207114,0.01428392,0.000009662615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9517934,0.01890611,0.01671827,0.0008574398,0.0005650716,0.0003589629,0.0009985981,0.0002490336,0.009553171],"genre_scores_gemma":[0.9657525,0.008419791,0.01583927,0.0003087476,0.0001012302,0.0001306187,0.0008102861,0.00004235439,0.008595323],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002074333,"threshold_uncertainty_score":0.006939352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2018457987184856,"score_gpt":0.4445192834387931,"score_spread":0.2426734847203075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}