{"id":"W4253993795","doi":"10.1210/me.14.5.718","title":"GCN5 and ADA Adaptor Proteins Regulate Triiodothyronine/GRIP1 and SRC-1 Coactivator-Dependent Gene Activation by the Human Thyroid Hormone Receptor","year":2000,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Coactivator; Nuclear receptor coactivator 3; Nuclear receptor coactivator 1; Biology; Nuclear receptor coactivator 2; Signal transducing adaptor protein; Cell biology; Nuclear receptor; Transcription factor; Molecular biology; Biochemistry; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008520672,0.0002461263,0.0001069743,0.00009458078,0.00009410506,0.0001853376,0.0001496235,0.0001402742,0.0009702426],"category_scores_gemma":[0.00007191532,0.0001250396,0.0002155699,0.00006903139,0.0001316101,0.00008319696,0.0001925586,0.0001821958,0.0003990457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003704724,"about_ca_system_score_gemma":0.0001347965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001686243,"about_ca_topic_score_gemma":0.003359331,"domain_scores_codex":[0.9999173,0.00001222003,0.000006914676,0.00001912131,0.00002102691,0.000023483],"domain_scores_gemma":[0.9999464,0.000005715423,0.00001778707,0.000005981686,0.00000465927,0.00001955268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008987889,0.000008332706,0.0003178641,0.00001024892,0.000003322446,0.00003411141,0.00001174132,0.00004678561,0.9989226,0.00005309195,0.00001496399,0.0004868768],"study_design_scores_gemma":[0.00003137053,0.0001397372,0.02052231,0.000005315369,0.0000141806,0.0003175784,0.00005583279,0.002340238,0.9742031,0.00005058833,0.002314222,0.00000562083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983585,0.0004584689,0.0006034164,0.00001943322,0.000005444895,0.000004006349,0.00008198671,0.00001757106,0.0004510777],"genre_scores_gemma":[0.997148,0.0001934235,0.0008636967,0.00002543834,0.00000218226,0.000007283411,0.0003636974,0.00001055711,0.001385807],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001686243,"threshold_uncertainty_score":0.003352821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004615954532033017,"score_gpt":0.2128687548264557,"score_spread":0.2082528002944227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}