{"id":"W4254172267","doi":"10.3410/f.1108756.564872","title":"Faculty Opinions recommendation of A genetic screen for dihydropyridine (DHP)-resistant worms reveals new residues required for DHP-blockage of mammalian calcium channels.","year":2008,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Center for Research Resources; Heart and Stroke Foundation of Canada","keywords":"Dihydropyridine; Calcium; Chemistry; Biology; Organic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001067981,0.00180523,0.001148485,0.003414925,0.0006512881,0.001624412,0.002468367,0.001634082,0.04389337],"category_scores_gemma":[0.006584533,0.0004946426,0.001119538,0.004092234,0.0002473831,0.0009091971,0.001127298,0.00159045,0.03965424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001230111,"about_ca_system_score_gemma":0.002393179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01943389,"about_ca_topic_score_gemma":0.04960985,"domain_scores_codex":[0.9990465,0.0001343367,0.0001007541,0.000210129,0.0003833626,0.000124852],"domain_scores_gemma":[0.9965703,0.001146249,0.0004408454,0.0005222307,0.0009312876,0.0003890575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001416995,0.0000445885,0.002194528,0.0008757506,0.00006411842,0.00005067281,0.00001713781,0.0003585932,0.0004514933,0.000274974,0.9905686,0.004957958],"study_design_scores_gemma":[0.0005816423,0.00004752882,0.01726855,0.0002757314,0.0001368063,0.0001333832,0.00006750436,0.001446648,0.002063777,0.0008268306,0.977106,0.00004556687],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0004045491,0.0000751473,0.00007968619,0.0001334605,0.00002162526,0.00001227797,0.9979042,0.0004061677,0.0009629644],"genre_scores_gemma":[0.0007293603,0.00006720678,0.00033861,0.00005727695,0.00000546,0.0000427357,0.997874,0.00004631622,0.000838978],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.04389337,"threshold_uncertainty_score":0.1468379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0464835145863562,"score_gpt":0.3456192848831294,"score_spread":0.2991357702967732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}