{"id":"W4254536002","doi":"10.1002/0471140864.ps0903s52","title":"Affinity Purification of Natural Ligands","year":2008,"lang":"en","type":"article","venue":"Current Protocols in Protein Science","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Biotechnology Research Institute","funders":"","keywords":"Chemistry; Cyanuric chloride; Cyanogen bromide; Covalent bond; Agarose; Glyoxal; Amine gas treating; Chloride; Nucleic acid; Ligand (biochemistry); Combinatorial chemistry; Polymer chemistry; Organic chemistry; Chromatography; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008058537,0.00009924749,0.0001078071,0.0001647985,0.0001380145,0.00002101713,0.0005610636,0.00005239408,0.00001514797],"category_scores_gemma":[0.0006480361,0.00008835107,0.0000398675,0.0007380617,0.0006687153,0.0000228582,0.0001722916,0.0001701135,0.00000991563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002879327,"about_ca_system_score_gemma":0.0005016307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007558956,"about_ca_topic_score_gemma":0.000006305234,"domain_scores_codex":[0.9985083,0.00004258278,0.0002803148,0.0003845624,0.0005079536,0.0002763186],"domain_scores_gemma":[0.9990837,0.000004958863,0.0001138881,0.0004309775,0.0002902783,0.0000762006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008040173,0.0001588441,0.006201643,0.00005334083,8.805279e-7,8.330668e-7,0.00005317221,0.0000108613,0.9824097,0.0004031256,0.00004490899,0.01058232],"study_design_scores_gemma":[0.0004919922,0.0001674615,0.01726511,0.00007893118,2.952858e-7,0.000005306671,0.00000782136,0.0001777612,0.9741908,0.0001219533,0.007385902,0.0001066703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9712499,0.0001507834,0.0003936373,0.00005070955,0.00005852156,0.02744544,0.000003448356,0.000009360355,0.0006382286],"genre_scores_gemma":[0.9734265,0.00001307674,0.0009827083,0.000006165613,0.00004370929,0.02533038,0.00000731847,0.000005721599,0.0001844183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01106346,"threshold_uncertainty_score":0.3602852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05586921261049506,"score_gpt":0.3798020435455521,"score_spread":0.3239328309350571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}