{"id":"W4254748045","doi":"10.1002/ange.201806412","title":"Surprising Antibacterial Activity and Selectivity of Hydrophilic Polyphosphoniums Featuring Sugar and Hydroxy Substituents","year":2018,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Antimicrobial agents and applications","field":"Chemistry","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Antibacterial activity; Chemistry; Staphylococcus aureus; Phosphonium; Bacteria; Escherichia coli; Polymer; Alkyl; Combinatorial chemistry; Gram-positive bacteria; Antibiotics; Organic chemistry; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007296101,0.0001679604,0.0002326767,0.00002637482,0.0001910389,0.00004154606,0.00009538607,0.0001192179,0.0001258243],"category_scores_gemma":[0.00002294837,0.000164842,0.00003531087,0.0001304876,0.0002918884,0.0001357632,0.0001259294,0.0001242564,0.000003483827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002827418,"about_ca_system_score_gemma":0.00002757727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006010948,"about_ca_topic_score_gemma":0.00007441258,"domain_scores_codex":[0.9991808,0.000006343956,0.0001415282,0.0003388161,0.00009925129,0.0002332776],"domain_scores_gemma":[0.9994783,0.00003333577,0.0001168726,0.0002217756,0.00005935496,0.00009032082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005224411,0.00006830082,0.009487751,0.00007575547,0.00003245759,0.000001748885,0.0001661472,6.920761e-8,0.9891197,0.00001742297,0.0001034086,0.0008749787],"study_design_scores_gemma":[0.0004137486,0.0000151928,0.01568273,0.00005351291,0.000034648,0.00002100191,0.0000122561,0.00001178772,0.982452,0.00003656449,0.001095045,0.0001715577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960617,0.0001141153,0.00002703206,0.00005232756,0.00004741107,0.0000632099,0.00004120306,0.00004414639,0.003548895],"genre_scores_gemma":[0.9991745,0.000121967,0.0001256714,0.00001817331,0.0002317668,0.000003532388,0.00001434555,0.00002081507,0.0002892002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006667756,"threshold_uncertainty_score":0.6722063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01048495356072862,"score_gpt":0.2318235836928811,"score_spread":0.2213386301321524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}