{"id":"W4254748045","doi":"10.1002/ange.201806412","title":"Surprising Antibacterial Activity and Selectivity of Hydrophilic Polyphosphoniums Featuring Sugar and Hydroxy Substituents","year":2018,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Antimicrobial agents and applications","field":"Chemistry","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Antibacterial activity; Chemistry; Staphylococcus aureus; Phosphonium; Bacteria; Escherichia coli; Polymer; Alkyl; Combinatorial chemistry; Gram-positive bacteria; Antibiotics; Organic chemistry; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001218464,0.0002003177,0.0001123334,0.00009752857,0.00007036262,0.0002370404,0.0001219988,0.0002591027,0.0007982396],"category_scores_gemma":[0.0001532801,0.0000999876,0.0000754409,0.00008212731,0.0002310313,0.0002005619,0.0001480254,0.0003192486,0.0001994783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009846134,"about_ca_system_score_gemma":0.00009426897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001957611,"about_ca_topic_score_gemma":0.0002384785,"domain_scores_codex":[0.9999264,0.00001212692,0.000004172296,0.00001538845,0.00001796879,0.00002383283],"domain_scores_gemma":[0.999904,0.00003946459,0.00002000685,0.000007542902,0.000009149693,0.00001973526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006723739,0.000007598672,0.00008617716,0.00003113899,0.00000177979,0.00003235544,0.00000712575,0.00006614411,0.998018,0.0001984161,0.00002724108,0.001456846],"study_design_scores_gemma":[0.000009901479,0.0002006094,0.0008985247,0.00000301818,0.000005704364,0.0001009575,0.000007486362,0.0004631297,0.9973664,0.00005364493,0.000888023,0.000002762949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949871,0.001130506,0.001152189,0.00008222545,0.00001980092,0.000008824781,0.00006652492,0.00002201461,0.00253087],"genre_scores_gemma":[0.9982552,0.0003573041,0.0007259292,0.00003697801,0.000008490728,0.000005526033,0.00004212045,0.000008797173,0.0005597082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007982396,"threshold_uncertainty_score":0.002670348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01048495356072862,"score_gpt":0.2318235836928811,"score_spread":0.2213386301321524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}