{"id":"W4254976957","doi":"10.1158/1538-7445.am2019-4529","title":"Abstract 4529: Mapping the protein interactome of mitochondrial intermembrane space proteases identifies a novel function for HTRA2","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Intermembrane space; Mitochondrial intermembrane space; Proteases; Biotinylation; Biology; Cell biology; Mitochondrion; Molecular biology; Biochemistry; Bacterial outer membrane; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000222723,0.0006043285,0.0006508187,0.000812753,0.0004813097,0.000853501,0.0002619222,0.0006915115,0.004071274],"category_scores_gemma":[0.000453927,0.0001836707,0.0007434351,0.0009974726,0.0001374111,0.0003656047,0.0003964493,0.0004882377,0.002666233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003616811,"about_ca_system_score_gemma":0.0002747267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001197655,"about_ca_topic_score_gemma":0.001654218,"domain_scores_codex":[0.9996132,0.00002981404,0.00002769299,0.0001693978,0.000105762,0.00005412798],"domain_scores_gemma":[0.9997644,0.00003879082,0.00008119812,0.0000234808,0.00003983532,0.00005232426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004714139,0.00003460753,0.01521365,0.0003313733,0.00009353206,0.0003482965,0.00004361862,0.0002279153,0.9765419,0.0001269113,0.001557573,0.005009444],"study_design_scores_gemma":[0.00009152113,0.0004653879,0.4041261,0.00008828545,0.0003507361,0.006905317,0.0002388602,0.01451458,0.5396206,0.0005210431,0.03301572,0.00006183912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9480452,0.007161914,0.0122081,0.0003933551,0.00007129285,0.00006520996,0.02850079,0.001013233,0.002540886],"genre_scores_gemma":[0.9098631,0.001981798,0.02009521,0.0003521377,0.00005168958,0.00007992984,0.06234415,0.0001705357,0.005061502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004071274,"threshold_uncertainty_score":0.01361972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07925075511544756,"score_gpt":0.3735900366515782,"score_spread":0.2943392815361306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}