{"id":"W4254979716","doi":"10.24124/2008/bpgub538","title":"Expression, purification and evaluation of recombinant human Syntaxin 18 as an endoribonuclease.","year":2008,"lang":"en","type":"dissertation","venue":"","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Heritage; Library and Archives Canada","funders":"","keywords":"Endoribonuclease; Recombinant DNA; RNA; Messenger RNA; Alanine scanning; Syntaxin; Yeast; Cleave; Biology; Cell biology; Mutant; Gene; Chemistry; Molecular biology; Computational biology; Biochemistry; Enzyme; RNase P; Membrane protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007305552,0.0003868417,0.0002859546,0.0002761684,0.0001720442,0.0004246712,0.0002144456,0.0002883806,0.0003909561],"category_scores_gemma":[0.0004129451,0.0001553,0.0003690886,0.0003464872,0.0001509564,0.0002376591,0.0001837311,0.0005134409,0.0005710421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003339572,"about_ca_system_score_gemma":0.0002839722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000327757,"about_ca_topic_score_gemma":0.0004230651,"domain_scores_codex":[0.9996808,0.0000817495,0.00004483811,0.00004909507,0.0001093933,0.00003415834],"domain_scores_gemma":[0.9998099,0.00003555208,0.00004660992,0.00002277743,0.00005626258,0.00002893679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003411382,0.00002930224,0.0001529212,0.0000398322,0.000005584596,0.00004923186,0.00002145714,0.0001241557,0.9981256,0.00007474915,0.00003882864,0.001304092],"study_design_scores_gemma":[0.00001273847,0.0002112625,0.0009993888,0.000009219923,0.00001812086,0.0003610622,0.00002834433,0.0007752567,0.9917705,0.00005593635,0.005752764,0.000005361556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9655709,0.004593018,0.02637442,0.000339959,0.00008285779,0.0002278225,0.001323832,0.0001159673,0.001371132],"genre_scores_gemma":[0.9137316,0.005413786,0.06380252,0.0001378763,0.00004758357,0.0002126273,0.008687595,0.0001042673,0.007862095],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007305552,"threshold_uncertainty_score":0.003863633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0251098717637902,"score_gpt":0.2999818354065223,"score_spread":0.2748719636427321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}