{"id":"W4255059068","doi":"10.4161/cbt.5.6.2958","title":"A Large Multi-Center Trial Attempting Individualized Therapy of Early Stage Breast Cancer Based on Predicted Risk of Recurrence","year":2006,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Breast cancer; Medicine; Clinical trial; Oncology; Internal medicine; Stage (stratigraphy); Cancer; Radiation therapy; Hormonal therapy; Chemotherapy; Family medicine; Gynecology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000385094,0.0002865925,0.0003976125,0.0001148453,0.00009569631,0.000009453986,0.0003620238,0.0003277395,0.0002510408],"category_scores_gemma":[0.00002324586,0.0002398486,0.0002010397,0.0002336567,0.0002838234,0.00000617064,0.00004123274,0.0001878686,9.144562e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007383007,"about_ca_system_score_gemma":0.0004811411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001046159,"about_ca_topic_score_gemma":0.0003015802,"domain_scores_codex":[0.9979827,0.000392178,0.0005308653,0.0005588763,0.0001602492,0.0003750953],"domain_scores_gemma":[0.9984604,0.00005484698,0.0006390611,0.0005177037,0.0002797212,0.00004824024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03593438,0.001443006,0.6657334,0.00002338863,0.0006159662,7.04151e-7,0.0003768909,0.0008232644,0.2719478,0.00002670808,0.0009494701,0.02212504],"study_design_scores_gemma":[0.2052757,0.004033359,0.3282754,0.0001949493,0.00006971638,0.000002028681,0.000102882,0.0006996028,0.4025256,0.00006612336,0.05788705,0.0008676507],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849623,0.004081231,0.001285934,0.0001422042,0.0006510746,0.0007962902,0.00800278,0.00002047634,0.00005764655],"genre_scores_gemma":[0.9913175,0.006241329,0.000561762,0.0003847815,0.0004884157,0.0004621922,0.0004193503,0.00004372602,0.00008101489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.337458,"threshold_uncertainty_score":0.9780743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02686137635653869,"score_gpt":0.3315447524769645,"score_spread":0.3046833761204258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}