{"id":"W4255097239","doi":"10.21203/rs.3.rs-538054/v1","title":"Efficacy of Fulvestrant in Women with Hormone-Resistant Metastatic Breast Cancer (mBC): A Canadian Province Experience","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Mach-Gaensslen Foundation of Canada; Saskatchewan Cancer Agency; University of Saskatchewan","keywords":"Fulvestrant; Metastatic breast cancer; Oncology; Medicine; Internal medicine; Breast cancer; Gynecology; Cancer; Estrogen receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000883096,0.0002458442,0.0004349428,0.00030569,0.001574125,0.0008126387,0.0005771404,0.0003340088,0.001846938],"category_scores_gemma":[0.002441576,0.0001322148,0.0003524154,0.001360207,0.0006013755,0.0002217282,0.0003206035,0.0006322002,0.0001935834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.02666128,"about_ca_system_score_gemma":0.03327379,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9416007,"about_ca_topic_score_gemma":0.9742198,"domain_scores_codex":[0.9995281,0.00007339069,0.00001769748,0.00003831949,0.000199216,0.0001432316],"domain_scores_gemma":[0.9989115,0.0001480926,0.0001131248,0.00002495833,0.0004436654,0.000358637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02907835,0.002914541,0.5704543,0.001042488,0.0005471763,0.002261283,0.007770383,0.002066793,0.009266408,0.002046348,0.02778877,0.3447632],"study_design_scores_gemma":[0.002928562,0.00505249,0.9444566,0.0003225228,0.0005309313,0.0009765654,0.005230134,0.0006153804,0.001094556,0.0003309887,0.03836931,0.00009188648],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9694983,0.009886372,0.0001221539,0.003920503,0.00007705107,0.0002226867,0.002153309,0.00001437089,0.01410521],"genre_scores_gemma":[0.9866675,0.007747698,0.0003951765,0.0006873775,0.0000497706,0.00003932821,0.001128288,0.00001645666,0.003268507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05839926,"threshold_uncertainty_score":0.193442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04034945561232564,"score_gpt":0.3822747702368161,"score_spread":0.3419253146244904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}