{"id":"W4255200503","doi":"10.1002/9780470249031.ch18","title":"Cytochrome P450 Enzymes","year":2007,"lang":"en","type":"other","venue":"","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Health Canada","keywords":"Enzyme; Cytochrome P450; Identification (biology); Computational biology; Biochemistry; Biology; Chemistry; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002465686,0.0009403783,0.0008478784,0.001376801,0.0003300542,0.00104706,0.0007529419,0.0007046762,0.1220657],"category_scores_gemma":[0.0004250979,0.0003284512,0.0006360957,0.001634851,0.0001862824,0.0007154639,0.000492678,0.00110653,0.1215015],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003624356,"about_ca_system_score_gemma":0.0005798769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001129623,"about_ca_topic_score_gemma":0.001770381,"domain_scores_codex":[0.9996606,0.00003166193,0.00002429638,0.0000703263,0.0001869841,0.00002607568],"domain_scores_gemma":[0.9998705,0.00002536499,0.00001679263,0.00001759931,0.00005950898,0.00001024449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006533117,0.0001165034,0.0004721376,0.001775878,0.00004093337,0.0002627917,0.00003345469,0.0001737633,0.0183445,0.005308786,0.3268575,0.6465484],"study_design_scores_gemma":[0.00001096357,0.00004498848,0.001152924,0.0001501996,0.00001480034,0.0005013684,0.000009319584,0.00004872664,0.005494291,0.0009447916,0.9916188,0.000008854086],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.004672748,0.2434876,0.03937902,0.004307024,0.005478301,0.0009166123,0.03775036,0.004368423,0.65964],"genre_scores_gemma":[0.01131469,0.1628864,0.0237603,0.002007733,0.002127182,0.000308414,0.02565882,0.0003671036,0.7715693],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.1220657,"threshold_uncertainty_score":0.4083504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.131058244352051,"score_gpt":0.4784674407459025,"score_spread":0.3474091963938516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}