{"id":"W4255681473","doi":"10.1089/hum.2014.154","title":"Ferret and Pig Models of Cystic Fibrosis: Prospects and Promise for Gene Therapy","year":2014,"lang":"en","type":"article","venue":"Human Gene Therapy Clinical Development","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institutes of Health","keywords":"Cystic fibrosis; Genetic enhancement; Medicine; Gene; Biology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004503488,0.000811806,0.001294649,0.001040108,0.00034443,0.001522226,0.001020244,0.002685789,0.004156516],"category_scores_gemma":[0.001287657,0.0003040423,0.0008248605,0.0004536722,0.001626217,0.00228675,0.0007055747,0.003193243,0.0007733296],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005334914,"about_ca_system_score_gemma":0.0007866027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004858347,"about_ca_topic_score_gemma":0.0008482719,"domain_scores_codex":[0.9992473,0.0004017227,0.00004952211,0.000078853,0.0001552405,0.00006737325],"domain_scores_gemma":[0.9991208,0.0004313596,0.0001215897,0.0001111494,0.00009402362,0.0001211447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003626663,0.001609669,0.003405019,0.004191668,0.0003046335,0.002550427,0.0005385948,0.002060788,0.4997848,0.06701998,0.03252923,0.3823785],"study_design_scores_gemma":[0.001217797,0.01656064,0.008475792,0.002603766,0.0005898227,0.01192817,0.0006841541,0.003890425,0.1336194,0.04621729,0.7739884,0.0002242653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.0933973,0.6423891,0.1694614,0.04993751,0.005941521,0.001074927,0.001967377,0.001830566,0.03400026],"genre_scores_gemma":[0.2047572,0.616227,0.1365251,0.01146014,0.001934139,0.001867036,0.003530091,0.0004384225,0.02326084],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004503488,"threshold_uncertainty_score":0.023817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06083135663043778,"score_gpt":0.3244637290561704,"score_spread":0.2636323724257326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}