{"id":"W4255681473","doi":"10.1089/hum.2014.154","title":"Ferret and Pig Models of Cystic Fibrosis: Prospects and Promise for Gene Therapy","year":2014,"lang":"en","type":"article","venue":"Human Gene Therapy Clinical Development","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institutes of Health","keywords":"Cystic fibrosis; Genetic enhancement; Medicine; Gene; Biology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007122562,0.0001885404,0.0002806179,0.0000278505,0.0001375924,0.00002108788,0.0001097848,0.0001594463,0.000004260582],"category_scores_gemma":[0.0000316,0.0001511403,0.00006892658,0.00003151446,0.0001511122,0.000003540896,0.000070961,0.00005979673,5.502493e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005932421,"about_ca_system_score_gemma":0.00007405849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002210459,"about_ca_topic_score_gemma":0.000003175859,"domain_scores_codex":[0.9985414,0.00007120114,0.0005034498,0.000575259,0.0001108716,0.0001978647],"domain_scores_gemma":[0.9993108,0.00002266143,0.0001641257,0.0002816862,0.0001204322,0.0001003135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008346123,0.0003002727,0.002257633,0.00004235884,0.0001616693,2.534635e-7,0.0002315407,0.00003765553,0.9477216,0.00021243,0.00014257,0.04805742],"study_design_scores_gemma":[0.004538557,0.005083698,0.07578205,0.00003482035,0.00002106293,0.00001173976,0.00002118607,0.000370205,0.8846392,0.003979068,0.0250365,0.0004818943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891313,0.004886497,0.005062837,0.00006630208,0.00009170213,0.0006951574,0.000005019687,0.00001075958,0.00005036978],"genre_scores_gemma":[0.9761526,0.004600854,0.01818911,0.0001692097,0.0003403589,0.00009986531,0.00005640699,0.0000328213,0.0003587859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07352442,"threshold_uncertainty_score":0.6163323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06083135663043778,"score_gpt":0.3244637290561704,"score_spread":0.2636323724257326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}