{"id":"W4256050296","doi":"10.21203/rs.2.107/v1","title":"Arthritis Prevention in the Pre-Clinical Phase of RA with Abatacept (the APIPPRA Study): A Multi-Centre, Randomised, Double Blind, Parallel Group Placebo-Controlled Clinical Trial","year":2018,"lang":"en","type":"preprint","venue":"Research Square","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Arthritis Society","funders":"","keywords":"Abatacept; Double blind; Medicine; Placebo; Rheumatoid arthritis; Clinical trial; Physical therapy; Arthritis; Single blind; Internal medicine; Randomized controlled trial; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003668199,0.003293839,0.008379625,0.0008240098,0.001064911,0.001987414,0.001497547,0.004010448,0.008103452],"category_scores_gemma":[0.003511278,0.001550998,0.003608232,0.0007572374,0.002262956,0.001743835,0.0009644961,0.004990858,0.001904507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007028211,"about_ca_system_score_gemma":0.00177677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008806881,"about_ca_topic_score_gemma":0.001142872,"domain_scores_codex":[0.9981452,0.0009734886,0.0001196165,0.0003122568,0.0001841388,0.0002652681],"domain_scores_gemma":[0.9979829,0.0006221515,0.0003847663,0.000239159,0.0001631165,0.0006079266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9901197,0.003281743,0.0001283926,0.0005263979,0.0004256118,0.00001857387,0.00002324758,0.00006777848,0.0007141902,0.00004694251,0.0002442552,0.004403138],"study_design_scores_gemma":[0.9699926,0.02871835,0.0005585068,0.0000219532,0.0002848474,0.00001391819,0.000006822728,0.000066294,0.00007966873,0.00006351236,0.000185557,0.000007899594],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9583393,0.0151468,0.001955787,0.001309167,0.002031647,0.01497475,0.00175037,0.0003355879,0.004156607],"genre_scores_gemma":[0.9545009,0.009031268,0.005146955,0.002131575,0.002709918,0.01891951,0.001733214,0.00007301456,0.005753719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008379625,"threshold_uncertainty_score":0.02710879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.191232001918822,"score_gpt":0.5104705807598413,"score_spread":0.3192385788410192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}