{"id":"W4256127173","doi":"10.1093/jnci/djg050","title":"Germline BRCA1 Mutations and a Basal Epithelial Phenotype in Breast Cancer","year":2003,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Cutaneous Melanoma Detection and Management","field":"Medicine","cited_by":961,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Jewish General Hospital","funders":"Norges Forskningsråd; Susan G. Komen for the Cure","keywords":"Breast cancer; Cytokeratin; Estrogen receptor; Germline; Phenotype; Germline mutation; Male breast cancer; Cancer research; Biology; Cancer; Internal medicine; Oncology; Pathology; Medicine; Mutation; Immunohistochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003616995,0.0001334271,0.000205108,0.0006436157,0.0003005278,0.0003569681,0.0001240052,0.0002313615,0.00138502],"category_scores_gemma":[0.001609197,0.0001379069,0.0001015841,0.000361511,0.0003465936,0.0001872828,0.0002570604,0.0002665775,0.0002163125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001885976,"about_ca_system_score_gemma":0.0001771906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001071722,"about_ca_topic_score_gemma":0.00164182,"domain_scores_codex":[0.999769,0.00004785885,0.00001816749,0.00004360101,0.00007937399,0.00004205807],"domain_scores_gemma":[0.9994169,0.0001275613,0.0002488603,0.00003835022,0.00003800977,0.0001302641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001967614,0.00003764491,0.9827182,0.00003673406,0.0000196959,0.002037166,0.00006790645,0.00005112681,0.005911772,0.00006583552,0.0001491031,0.00870801],"study_design_scores_gemma":[0.000007220334,0.00008819519,0.9791896,0.00001699841,0.00002372415,0.01859914,0.00008881134,0.0001030825,0.00149679,0.00009973069,0.0002829846,0.00000366107],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980652,0.0008232066,0.0001526316,0.00005121123,0.000003666334,0.000007004509,0.0000597055,0.000007552028,0.0008297137],"genre_scores_gemma":[0.999404,0.0002345986,0.0001339203,0.00002056302,0.000006481681,0.000001983365,0.00008388723,0.000001429385,0.0001132906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00138502,"threshold_uncertainty_score":0.004633427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02738752693384942,"score_gpt":0.314240971318956,"score_spread":0.2868534443851065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}