{"id":"W4256170893","doi":"10.32920/ryerson.14657247","title":"A Novel Transcription-Interference Mechanism To Suppress Checkpoint","year":2021,"lang":"en","type":"preprint","venue":"","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trent University; Toronto Metropolitan University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Schizosaccharomyces pombe; G2-M DNA damage checkpoint; Homologous recombination; Biology; DNA repair; DNA damage; Genetics; Schizosaccharomyces; Chromosome segregation; Cell biology; Cell cycle checkpoint; CHEK1; Gene; Gene silencing; RNA interference; Prophase; Meiosis; Transcription factor; DNA; Saccharomyces cerevisiae; Cell cycle; Chromosome; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002861665,0.000605256,0.0004196923,0.0002762316,0.0003525238,0.0006631144,0.0008164498,0.0005876222,0.003080233],"category_scores_gemma":[0.000257853,0.0002650546,0.0006233093,0.0001736233,0.0004770661,0.000490483,0.0005422015,0.001083015,0.001368515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005000102,"about_ca_system_score_gemma":0.0003119611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002034436,"about_ca_topic_score_gemma":0.0002939266,"domain_scores_codex":[0.9995419,0.00002458425,0.00002402398,0.0002109063,0.000134388,0.00006414936],"domain_scores_gemma":[0.9998073,0.00003059253,0.00004150601,0.00005536999,0.00002917888,0.00003613169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004180475,0.00004389845,0.0001461873,0.0000413973,0.000008833466,0.00008101991,0.00001739198,0.0001220227,0.990074,0.003254284,0.0002157288,0.005953377],"study_design_scores_gemma":[0.00004272827,0.0001874205,0.0005879213,0.000005255925,0.00002842172,0.0005448447,0.000008895468,0.004655944,0.9792809,0.001060893,0.01358053,0.00001637766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4645132,0.01064644,0.4840389,0.00163257,0.001942386,0.0005281912,0.001036013,0.005247381,0.03041483],"genre_scores_gemma":[0.8623661,0.00174157,0.1029822,0.0007728843,0.0002399703,0.0002856934,0.0009586661,0.0003475991,0.03030546],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003080233,"threshold_uncertainty_score":0.01030433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02128936898025667,"score_gpt":0.2564117224836892,"score_spread":0.2351223535034325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}