{"id":"W4256199628","doi":"10.3410/f.736865748.793580851","title":"Faculty Opinions recommendation of PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation.","year":2020,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"PTEN; Tensin; Cancer research; Carcinogenesis; Phosphatase; Biology; Cell biology; Gene; Genetics; PI3K/AKT/mTOR pathway; Signal transduction; Phosphorylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007808465,0.001321101,0.00123603,0.00335729,0.0006975809,0.00195061,0.001777476,0.0009636309,0.06486566],"category_scores_gemma":[0.006897113,0.0003225878,0.001287836,0.006767699,0.0002505665,0.001034079,0.00153256,0.001134299,0.03689616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001575352,"about_ca_system_score_gemma":0.003433137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02319489,"about_ca_topic_score_gemma":0.06049275,"domain_scores_codex":[0.9989785,0.0001737149,0.000133375,0.0002847649,0.0002845498,0.0001451359],"domain_scores_gemma":[0.9972684,0.0007587001,0.0004962024,0.0002701529,0.0008065591,0.0003999544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001960122,0.00002001079,0.00444056,0.003946815,0.0001772209,0.00004830514,0.00003568986,0.0002488727,0.0004063,0.0005039957,0.9803839,0.009592417],"study_design_scores_gemma":[0.0003002635,0.00002901348,0.01756884,0.0007633141,0.000169663,0.00009021351,0.00007434808,0.0003486639,0.0007703103,0.000700977,0.9791521,0.00003225463],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0005028556,0.0005110383,0.00004563075,0.0002414919,0.0000404374,0.00001776469,0.996371,0.0002245095,0.002045305],"genre_scores_gemma":[0.001861123,0.000503734,0.0003326597,0.0001065729,0.00001607797,0.00006473476,0.9953236,0.00005514839,0.001736335],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.06486566,"threshold_uncertainty_score":0.2169972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03383587364044016,"score_gpt":0.3481116429344674,"score_spread":0.3142757692940273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}