{"id":"W4256446122","doi":"10.1158/2159-8290.cd-nb2019-113","title":"Collaborative Review, Concurrent Approval","year":2019,"lang":"en","type":"article","venue":"Cancer Discovery","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Pembrolizumab; Lenvatinib; Drug approval; Medicine; Drug; Cancer; Oncology; Pharmacology; Internal medicine; Immunotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006297032,0.0001422627,0.0004183159,0.000038253,0.00002214863,0.00001803291,0.0000632872,0.00003904693,0.001664838],"category_scores_gemma":[0.00003540004,0.00009853025,0.0001194836,0.0004807317,0.00003851039,0.0001681147,0.0000331319,0.000114418,0.000280409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002343265,"about_ca_system_score_gemma":0.0003327267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004689507,"about_ca_topic_score_gemma":0.000006679565,"domain_scores_codex":[0.9990367,0.00002569987,0.0001913243,0.0002793951,0.0002713505,0.0001955212],"domain_scores_gemma":[0.9994448,0.0000415604,0.00007634851,0.0002241151,0.0001038517,0.000109335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003609091,0.001958978,0.3859668,0.01880534,0.002695155,0.0001728017,0.0005849396,0.00003370133,0.008859127,0.009065253,0.2024003,0.3658485],"study_design_scores_gemma":[0.01851216,0.001831471,0.06314032,0.01016932,0.001299448,0.00002648631,0.0003070368,0.00002838502,0.01393775,0.0002249071,0.889736,0.0007867327],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4828396,0.4136808,0.00009129785,0.006345173,0.004228397,0.003840434,0.0004289545,0.0001158509,0.0884295],"genre_scores_gemma":[0.9270967,0.04703858,0.00004290025,0.00689498,0.0005142146,0.0003531816,0.0001083028,0.00002740583,0.01792379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6873357,"threshold_uncertainty_score":0.9992478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01697361601396653,"score_gpt":0.3264949462644223,"score_spread":0.3095213302504558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}