{"id":"W4256589481","doi":"10.1139/v02-004","title":"Enantioselective enzymatic aminolysis of a racemic 2-isoxazolylacetate alkyl ester","year":2002,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Aminolysis; Chemistry; Lipase; Enantioselective synthesis; Amide; Alkyl; Candida antarctica; Stereochemistry; Organic chemistry; Pseudomonas; Enzyme; Catalysis; Bacteria","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000223039,0.0005163589,0.0002580256,0.0001968242,0.0001115663,0.0002179871,0.0002313354,0.0003092071,0.0008301032],"category_scores_gemma":[0.0001622236,0.000130732,0.0002194023,0.0001961703,0.0001409468,0.0001831391,0.0002131935,0.0003626928,0.0007459774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003048277,"about_ca_system_score_gemma":0.0002632135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008471871,"about_ca_topic_score_gemma":0.001417766,"domain_scores_codex":[0.9998023,0.00003416435,0.00001579306,0.00003051982,0.00006041888,0.00005676364],"domain_scores_gemma":[0.9999341,0.00001199997,0.00002139409,0.000009331024,0.00001316024,0.00001013319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004974687,0.00001176119,0.00004727458,0.00001573533,0.000002770086,0.00005423863,0.000006503415,0.00005257244,0.9985237,0.00008239449,0.0000260387,0.001127268],"study_design_scores_gemma":[0.000006973127,0.00007422484,0.0002832561,0.000001861254,0.000004977043,0.0001377872,0.000006255722,0.0002035733,0.9980943,0.00001243731,0.001171504,0.000002843259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9673391,0.002828466,0.02120513,0.0002444327,0.00009109165,0.00008770789,0.000408855,0.0001835925,0.007611652],"genre_scores_gemma":[0.9799649,0.00186211,0.01028562,0.00007082722,0.00001585471,0.00004822743,0.0006430165,0.00003732254,0.007072187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008471871,"threshold_uncertainty_score":0.00277698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008187539347437546,"score_gpt":0.1962149309454984,"score_spread":0.1880273915980608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}