{"id":"W4256754952","doi":"10.1016/s0959-8049(02)81121-2","title":"Phase II study of the DNA methyltransferase I (DNMT1) inhibitor MG98 in patients (pts) with renal cell carcinoma (RCC). A trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG)","year":2002,"lang":"en","type":"article","venue":"European Journal of Cancer","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Renal cell carcinoma; Medicine; Clinical trial; Internal medicine; Oncology; Cancer; DNMT1; Methyltransferase; DNA; Biology; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000792399,0.001782369,0.002189684,0.0003823428,0.0005016484,0.0009675001,0.001024824,0.001571068,0.00436232],"category_scores_gemma":[0.001074385,0.0006752933,0.001168175,0.0005107141,0.0008605008,0.0007385655,0.0003906493,0.003586111,0.0009951859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001150212,"about_ca_system_score_gemma":0.001720974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004015198,"about_ca_topic_score_gemma":0.01025609,"domain_scores_codex":[0.9997655,0.0001042478,0.00000760961,0.00004052999,0.00002070018,0.00006143676],"domain_scores_gemma":[0.9993271,0.00009073092,0.0001084068,0.00004638711,0.00003169843,0.0003957619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8675018,0.02743889,0.004540488,0.0005338015,0.0009732829,0.0002589279,0.0002240616,0.002003009,0.02011898,0.000314281,0.007182842,0.06890977],"study_design_scores_gemma":[0.8342078,0.151297,0.008697221,0.00002581102,0.0003777753,0.0002098348,0.00006410485,0.0008052564,0.00171835,0.0002186695,0.002354164,0.00002399665],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898839,0.002641182,0.0003948467,0.001228979,0.0002868131,0.001514966,0.001603216,0.0001324335,0.00231352],"genre_scores_gemma":[0.985153,0.002765664,0.001194393,0.00126233,0.0002590151,0.001452365,0.003171887,0.00004311841,0.004698128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00436232,"threshold_uncertainty_score":0.01459342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05604389073097916,"score_gpt":0.3342235457670223,"score_spread":0.2781796550360432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}