{"id":"W4280488291","doi":"10.1242/dmm.049544","title":"<i>Snrpb</i> is required in murine neural crest cells for proper splicing and craniofacial morphogenesis","year":2022,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Azrieli Foundation; McGill University Health Centre","keywords":"Neural crest; Biology; Craniofacial; Exon; Cranial neural crest; Intron; Morphogenesis; Cell biology; RNA splicing; Genetics; Embryo; Gene; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009327143,0.0002709466,0.0001517849,0.0002591852,0.0001817682,0.0002786867,0.0002026122,0.0002580537,0.001400698],"category_scores_gemma":[0.000145567,0.0002526047,0.0001452348,0.00009249501,0.0002323558,0.0001035305,0.0002062022,0.0003221302,0.0008323844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001828196,"about_ca_system_score_gemma":0.0001543372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009581822,"about_ca_topic_score_gemma":0.001975337,"domain_scores_codex":[0.9998364,0.00002272112,0.00002312204,0.00003021561,0.00005432699,0.00003307932],"domain_scores_gemma":[0.9996841,0.00003713438,0.0001517415,0.00002828801,0.00001759351,0.00008110693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003835513,0.000004628955,0.0002095507,0.000006800056,0.000001544069,0.0001235635,0.000007007774,0.0000269287,0.9989724,0.00007234664,0.00001653773,0.0005203273],"study_design_scores_gemma":[0.00001384944,0.0001675187,0.01189716,0.000008190518,0.00001381245,0.0009871654,0.00003610171,0.0008733515,0.983566,0.00007020438,0.002362101,0.000004490987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994943,0.0003914388,0.002252775,0.00005362248,0.00001429766,0.00001250116,0.0003528526,0.0001305611,0.001848837],"genre_scores_gemma":[0.9943928,0.0002123065,0.001933437,0.00002875745,0.000006070382,0.00001860657,0.000650701,0.00007845584,0.002678949],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001400698,"threshold_uncertainty_score":0.004685819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0203032048140045,"score_gpt":0.2493875405209024,"score_spread":0.2290843357068979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}