{"id":"W4280493587","doi":"10.1101/2022.05.06.490995","title":"Highly specialized carbohydrate metabolism capability in <i>Bifidobacterium</i> strain associated with intestinal barrier maturation in early preterm infants","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Infant Nutrition and Health","field":"Nursing","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; University of Calgary; Institute for Clinical and Translational Research, University of Wisconsin, Madison; Gerber Foundation","keywords":"Necrotizing enterocolitis; Bifidobacterium; Biology; Microbiome; Bifidobacterium breve; Intestinal permeability; Gut flora; Barrier function; Calprotectin; Metagenomics; Microbiology; Immunology; Bioinformatics; Medicine; Internal medicine; Gene; Bacteria; Genetics; Lactobacillus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002807712,0.0003367579,0.0004129558,0.0005306729,0.0003534597,0.0007978981,0.0002097097,0.0003256484,0.0009169372],"category_scores_gemma":[0.0007408353,0.0002043477,0.0003942844,0.0005593238,0.0002156087,0.0002090172,0.000562068,0.0004498316,0.0002254548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002573318,"about_ca_system_score_gemma":0.0002701052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003912041,"about_ca_topic_score_gemma":0.003246906,"domain_scores_codex":[0.9996954,0.00004412585,0.00002819065,0.00009747545,0.00005809235,0.00007669872],"domain_scores_gemma":[0.9996352,0.00004166559,0.0001575551,0.00003117532,0.0000620594,0.00007228695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008955617,0.00009366382,0.5124798,0.0001357213,0.0001695216,0.0004261569,0.0003709699,0.0001580958,0.4757849,0.0001262363,0.0002317796,0.009127601],"study_design_scores_gemma":[0.000003383523,0.0001739663,0.983646,0.00002579943,0.00007141865,0.0006712214,0.0004524551,0.0003365639,0.01388346,0.00008023752,0.0006438848,0.00001159778],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980903,0.0003914016,0.0004552589,0.00004387136,0.000006490284,0.000007929518,0.000730522,0.000009819693,0.0002643492],"genre_scores_gemma":[0.997817,0.0002054182,0.0008614809,0.00005454144,0.000004642295,0.00001251411,0.0008180736,0.0000106718,0.0002156602],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003912041,"threshold_uncertainty_score":0.007778525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01346696999165355,"score_gpt":0.2364627046455263,"score_spread":0.2229957346538728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}