{"id":"W4280501079","doi":"10.1177/20552173221086662","title":"Fecal microbiota transplantation is safe and tolerable in patients with multiple sclerosis: A pilot randomized controlled trial","year":2022,"lang":"en","type":"article","venue":"Multiple Sclerosis Journal - Experimental Translational and Clinical","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; St Joseph's Health Care; Lawson Health Research Institute; London Health Sciences Centre; Western University","funders":"London Health Sciences Foundation","keywords":"Medicine; Intestinal permeability; Multiple sclerosis; Gut flora; Gastroenterology; Internal medicine; Randomized controlled trial; Transplantation; Feces; Fecal bacteriotherapy; Immunology; Biology; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001131502,0.0002619415,0.0007942953,0.00009071435,0.0005200567,0.00007678158,0.0001190363,0.0001163553,0.0001451991],"category_scores_gemma":[0.00004558271,0.0002093322,0.0002831707,0.00008242943,0.0002273065,0.00002720353,0.00004208947,0.0004100349,0.000001264949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003092541,"about_ca_system_score_gemma":0.0001121247,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000414432,"about_ca_topic_score_gemma":0.0000436284,"domain_scores_codex":[0.9971184,0.0007120371,0.001091531,0.0004715225,0.0003037022,0.0003028728],"domain_scores_gemma":[0.9990658,0.0002956331,0.0002720829,0.0001079625,0.00006316769,0.0001953089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8779975,0.002074062,0.04566634,0.00001164151,0.0002109557,0.000001749299,0.0003762929,0.0000559287,0.07317035,0.000014593,0.00008900656,0.000331556],"study_design_scores_gemma":[0.8509564,0.002858719,0.1436997,0.00005587052,0.00008361378,0.0000204305,0.0001406283,0.0002586825,0.001504932,0.00001506553,0.0001472909,0.0002586348],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995563,0.00140189,0.000153656,0.0004771213,0.0002757483,0.001933761,0.0001531891,0.000006494303,0.00003517549],"genre_scores_gemma":[0.9968836,0.0008386943,0.00098349,0.0006758213,0.0001582723,0.0001808618,0.0002106518,0.00002584138,0.00004273532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09803335,"threshold_uncertainty_score":0.8536321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04497412016135997,"score_gpt":0.2874829487925395,"score_spread":0.2425088286311795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}