{"id":"W4280501942","doi":"10.1016/j.celrep.2022.110802","title":"Adipose mitochondrial metabolism controls body growth by modulating systemic cytokine and insulin signaling","year":2022,"lang":"en","type":"article","venue":"Cell Reports","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Adipose tissue; Cytokine; Insulin; Metabolism; Insulin receptor; Signal transduction; Endocrinology; Cell biology; Internal medicine; Biology; Insulin resistance; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007954214,0.0002743273,0.0001572163,0.0001624973,0.0001060627,0.0003786381,0.0001344944,0.0001723826,0.0006795615],"category_scores_gemma":[0.0000658507,0.0001043806,0.0001305328,0.00009630092,0.0002662531,0.0002407634,0.0002702183,0.0003135572,0.0001747747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002956553,"about_ca_system_score_gemma":0.0001484834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000317444,"about_ca_topic_score_gemma":0.0008427579,"domain_scores_codex":[0.9999241,0.00001035275,0.000005822031,0.00002692203,0.00001699983,0.00001580894],"domain_scores_gemma":[0.9999182,0.000006316392,0.00003300085,0.000008825267,0.000008668516,0.00002494934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005146479,0.000003380086,0.0003357946,0.00001327472,0.000002110167,0.00002259801,0.000005958885,0.00004054117,0.9986059,0.00009344459,0.00001485003,0.0008106519],"study_design_scores_gemma":[0.00002479643,0.0001881324,0.02559371,0.00001488398,0.00003132709,0.000225261,0.00009597177,0.00186974,0.9686547,0.0002007254,0.003091834,0.000008890166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864174,0.002947064,0.007518077,0.0001578517,0.00003591436,0.0000173827,0.0003068869,0.0001040529,0.002495483],"genre_scores_gemma":[0.9942254,0.001348297,0.002496845,0.00004203276,0.000009202041,0.00001442571,0.0001459699,0.00002259988,0.001695231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006795615,"threshold_uncertainty_score":0.002273321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008339278594695155,"score_gpt":0.2280676905945577,"score_spread":0.2197284119998625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}