{"id":"W4280501942","doi":"10.1016/j.celrep.2022.110802","title":"Adipose mitochondrial metabolism controls body growth by modulating systemic cytokine and insulin signaling","year":2022,"lang":"en","type":"article","venue":"Cell Reports","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Adipose tissue; Cytokine; Insulin; Metabolism; Insulin receptor; Signal transduction; Endocrinology; Cell biology; Internal medicine; Biology; Insulin resistance; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005108679,0.0002756212,0.0007659225,0.0001427283,0.0003067617,0.00003492145,0.00007528837,0.00009718013,0.0002148923],"category_scores_gemma":[0.0002381266,0.000262762,0.0001362767,0.0002252145,0.00004968474,0.0001089223,0.0001497032,0.0004392688,0.000006042872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006057693,"about_ca_system_score_gemma":0.0001359465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001560492,"about_ca_topic_score_gemma":4.284353e-7,"domain_scores_codex":[0.9974529,0.0001372495,0.0008226755,0.0006021721,0.0005695848,0.0004154637],"domain_scores_gemma":[0.9985501,0.00008687808,0.0005043966,0.0004341258,0.0001230756,0.000301461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000168027,0.0001446301,0.001110177,0.0001313321,0.0001213066,0.002208507,0.000523991,0.00005172388,0.9920526,0.00009845183,0.002290577,0.001098732],"study_design_scores_gemma":[0.01625071,0.0008307759,0.004066874,0.000317828,0.004359199,0.02820346,0.001132693,0.001900565,0.5702709,0.001148943,0.3698271,0.00169097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9534184,0.0419406,0.0003655615,0.0001287218,0.001255691,0.001003383,0.00002923373,0.0001292546,0.001729164],"genre_scores_gemma":[0.9944713,0.0001608948,0.0006550599,0.0003750984,0.0008635102,0.0001354415,0.0001354053,0.00006823536,0.003135051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4217816,"threshold_uncertainty_score":0.9999825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008339278594695155,"score_gpt":0.2280676905945577,"score_spread":0.2197284119998625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}