{"id":"W4280504666","doi":"10.3389/fimmu.2022.897223","title":"Assessment of the Safety and Efficacy of an Oral Probiotic-Based Vaccine Against Aspergillus Infection in Captive-Bred Humboldt Penguins (Spheniscus humboldti)","year":2022,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Coccidia and coccidiosis research","field":"Agricultural and Biological Sciences","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Muséum National d'Histoire Naturelle; Agence Nationale de la Recherche","keywords":"Aspergillus fumigatus; Biology; Aspergillosis; Immunity; Vaccination; Aspergillus; Immunology; Microbiology; Antibody; Placebo; Immune system; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002747746,0.000349968,0.0004486491,0.0001634368,0.0001544407,0.0002238302,0.0002023936,0.0004612403,0.000612095],"category_scores_gemma":[0.000353284,0.00009246168,0.0001897847,0.00008043211,0.0003458918,0.0002302467,0.0001420972,0.0004086794,0.0001096293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002126918,"about_ca_system_score_gemma":0.0001861388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008192112,"about_ca_topic_score_gemma":0.001236115,"domain_scores_codex":[0.9998378,0.00004048394,0.00001160026,0.00004204785,0.00003927702,0.00002878955],"domain_scores_gemma":[0.9997422,0.00004421149,0.00006759955,0.00002115549,0.00003565887,0.00008916797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02693208,0.007653533,0.0200809,0.0006918708,0.0001630048,0.0003073679,0.0003807021,0.0004669404,0.9002788,0.00006960663,0.000204766,0.04277048],"study_design_scores_gemma":[0.001553147,0.5843534,0.1946184,0.00006232956,0.0003386817,0.0006717077,0.0005800783,0.001052885,0.213527,0.00008572391,0.003116857,0.00003976394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999403,0.0003105032,0.00008828981,0.00001831704,0.00001018828,0.0000357429,0.00003903578,0.000003600357,0.00009125737],"genre_scores_gemma":[0.9985648,0.0003484548,0.0003509832,0.00006332703,0.00001725301,0.00007292658,0.0001154453,0.000001385506,0.000465398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008192112,"threshold_uncertainty_score":0.002047718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01119938514061858,"score_gpt":0.2493340840017874,"score_spread":0.2381346988611689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}