{"id":"W4280509433","doi":"10.3390/curroncol29050293","title":"CAR T Cell Therapy for Chronic Lymphocytic Leukemia: Successes and Shortcomings","year":2022,"lang":"en","type":"review","venue":"Current Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fakultet Medicinskih Nauka, Univerziteta U Kragujevcu; Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja","keywords":"Chimeric antigen receptor; Chronic lymphocytic leukemia; Medicine; CAR T-cell therapy; Leukemia; Lymphoma; Cancer research; T cell; Cell therapy; Immunology; Cell; Immune system; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006906307,0.0005509543,0.002762602,0.000403587,0.0001825667,0.00003200814,0.0004013723,0.0004713286,0.004690477],"category_scores_gemma":[0.00009704542,0.0004468082,0.0006621395,0.0003612874,0.0002521959,0.00003977838,0.0002664951,0.001126625,0.00002570121],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.02207929,"about_ca_system_score_gemma":0.01936755,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005109579,"about_ca_topic_score_gemma":0.00001765114,"domain_scores_codex":[0.9970468,0.0003259364,0.0006887523,0.0008506714,0.0003657248,0.0007221077],"domain_scores_gemma":[0.997139,0.001595624,0.0003168942,0.0005872866,0.00009497994,0.0002661622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001614516,0.000113632,0.000008446247,0.02946086,0.0002049695,0.00004781344,0.00009574618,4.473455e-7,0.00002189041,0.00002000348,0.005029805,0.9648349],"study_design_scores_gemma":[0.003866392,0.002594431,0.00000112456,0.001319208,0.0008460077,0.0003626512,0.0000303917,0.00005570628,0.00001972981,0.00001690414,0.9905387,0.0003487993],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002969174,0.9918791,0.00001392036,0.00004445771,0.001612505,0.004337267,0.00008612347,0.00007363234,0.001656084],"genre_scores_gemma":[0.00001333078,0.9914847,0.0000360594,0.00006209226,0.001277744,0.002591698,0.0005826161,0.0001483674,0.003803394],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9855089,"threshold_uncertainty_score":0.9997984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2212568359031883,"score_gpt":0.4845948981931005,"score_spread":0.2633380622899121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}