{"id":"W4280511624","doi":"10.7554/elife.73523","title":"Inositol polyphosphate multikinase physically binds to the SWI/SNF complex and modulates BRG1 occupancy in mouse embryonic stem cells","year":2022,"lang":"en","type":"article","venue":"eLife","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kootenay Association for Science & Technology","funders":"National Research Foundation of Korea","keywords":"SWI/SNF; Chromatin immunoprecipitation; SMARCB1; Cell biology; Transcription factor; Chromatin; Biology; Transcriptional regulation; Chromatin remodeling; Molecular biology; Chemistry; Promoter; Genetics; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001173994,0.00022009,0.0002089213,0.0003679359,0.0001510981,0.0003173003,0.0002433632,0.0002440135,0.001205054],"category_scores_gemma":[0.00007388632,0.0002696385,0.0002051446,0.0002315296,0.0002183547,0.0001305499,0.0002375764,0.0004666281,0.0005270254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005302585,"about_ca_system_score_gemma":0.0001933296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002192867,"about_ca_topic_score_gemma":0.004444,"domain_scores_codex":[0.9998314,0.00001381846,0.00001118485,0.00004772319,0.00005624898,0.00003955297],"domain_scores_gemma":[0.9999385,0.000006091797,0.00001985514,0.000005949642,0.000006002348,0.00002361087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003786769,0.000005011458,0.0002614837,0.00001107564,0.00000232114,0.0000164565,0.000008286779,0.00002491418,0.9988938,0.00006342371,0.00004689835,0.0006286463],"study_design_scores_gemma":[0.00002038112,0.00006728809,0.03721993,0.000007031353,0.00001392096,0.00009480675,0.00004033019,0.001221878,0.957892,0.00005596847,0.003361723,0.000004874662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908054,0.002454762,0.002748928,0.0001711369,0.00002886164,0.00001938659,0.001162359,0.0001923259,0.002416725],"genre_scores_gemma":[0.9907756,0.001141194,0.001612328,0.0001238608,0.000005353844,0.00003060583,0.001509087,0.0000551852,0.004746841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002192867,"threshold_uncertainty_score":0.004360199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01280482073671803,"score_gpt":0.2468515606319173,"score_spread":0.2340467398951993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}