{"id":"W4280518096","doi":"10.1016/j.ejcb.2022.151237","title":"MeCP2 and transcriptional control of eukaryotic gene expression","year":2022,"lang":"en","type":"article","venue":"European Journal of Cell Biology","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Chromatin; Epigenetics; Regulation of gene expression; ChIA-PET; Chromatin remodeling; Enhancer; Genetics; MECP2; Gene expression; Gene; Cell biology; Histone; Transcriptional regulation; DNA methylation; Epigenetics of physical exercise; Computational biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001227,0.0002553926,0.0001365899,0.0003366208,0.0001120619,0.0004019018,0.0002328071,0.0003443269,0.0004170116],"category_scores_gemma":[0.00007844694,0.00008715491,0.0001024228,0.0003348719,0.0003360791,0.0002670028,0.0003123015,0.0004395965,0.0002290953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004909128,"about_ca_system_score_gemma":0.0002135029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001500429,"about_ca_topic_score_gemma":0.001426003,"domain_scores_codex":[0.9999163,0.00001595967,0.000005438417,0.00002415347,0.00002048026,0.00001758743],"domain_scores_gemma":[0.9999729,0.000006525438,0.000008048224,0.000001690104,0.000003809846,0.000006911126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005218913,0.00004674794,0.003201056,0.001797003,0.00006867126,0.002693656,0.0002574337,0.001913474,0.7084857,0.03021965,0.003703911,0.2470909],"study_design_scores_gemma":[0.00005298205,0.0002977901,0.0468383,0.0003403903,0.00009295279,0.007634474,0.000319177,0.003166877,0.3829698,0.02879808,0.5294085,0.00008086082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1323952,0.8338899,0.01200866,0.001587484,0.0001946633,0.00002674578,0.0004681714,0.0001650297,0.01926418],"genre_scores_gemma":[0.6133495,0.3539181,0.008464516,0.0008024505,0.0004713954,0.00006322184,0.0009625765,0.00004494092,0.02192331],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001500429,"threshold_uncertainty_score":0.003561854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007119741144267814,"score_gpt":0.1914770752216877,"score_spread":0.1843573340774199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}