{"id":"W4280519323","doi":"10.1007/s13258-022-01258-5","title":"TFPI inhibits breast cancer progression by suppressing ERK/p38 MAPK signaling pathway","year":2022,"lang":"en","type":"article","venue":"Genes & Genomics","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Women and Children's Health Research Institute","keywords":"Biology; MAPK/ERK pathway; Breast cancer; Cancer research; p38 mitogen-activated protein kinases; Signal transduction; Cancer; Cell biology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002405929,0.0002024364,0.0002944068,0.00009130716,0.0004599741,0.00004587836,0.0001369013,0.00008124619,0.001203778],"category_scores_gemma":[0.000003801532,0.0001994846,0.0001028929,0.0002029736,0.00003098452,0.00006610936,0.0002303382,0.0002449983,0.00002061162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002294214,"about_ca_system_score_gemma":0.0002455901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002205639,"about_ca_topic_score_gemma":0.00000376045,"domain_scores_codex":[0.9984624,0.00008035929,0.0003200512,0.00039128,0.0003871317,0.0003587112],"domain_scores_gemma":[0.9992887,0.00001754238,0.0001666854,0.0002820575,0.000074908,0.0001701117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009938313,0.0001613906,0.001520193,0.00004316171,0.00005133852,0.0000115816,0.0004225578,0.0005419583,0.880268,0.00007435715,0.001167765,0.1156383],"study_design_scores_gemma":[0.0016666,0.0001709241,0.001086288,0.00009383365,0.0001394356,0.0001988376,0.0006349858,0.001650716,0.879449,0.0002845285,0.1142698,0.0003550889],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904157,0.006218911,0.0003453249,0.001171239,0.0006350769,0.000477173,0.0003300099,0.0001318057,0.0002747801],"genre_scores_gemma":[0.9953237,0.000138549,0.001835332,0.001268362,0.0003674777,0.0001332995,0.00025242,0.00007596699,0.0006048553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1152832,"threshold_uncertainty_score":0.9997092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02097859213259569,"score_gpt":0.2756446490949074,"score_spread":0.2546660569623117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}