{"id":"W4280519978","doi":"10.1016/j.orcp.2022.04.004","title":"The missense variant, rs373863828, in CREBRF plays a role in longitudinal changes in body mass index in Samoans","year":2022,"lang":"en","type":"article","venue":"Obesity Research & Clinical Practice","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Childhood Cancer Canada; National Institutes of Health; Ministry of Health; National Heart, Lung, and Blood Institute; National Institute of Environmental Health Sciences; University of Cincinnati","keywords":"Missense mutation; Index (typography); Body mass index; Biology; Medicine; Internal medicine; Genetics; Mutation; Gene; Computer science; World Wide Web","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","research_integrity"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.02901373,0.0001517481,0.0003591619,0.0002292592,0.0002681491,0.00004333543,0.0005847071,0.0003182169,0.00006671539],"category_scores_gemma":[0.03038706,0.0001416241,0.00007631117,0.0008278757,0.0002141239,0.00001416035,0.0007888589,0.002314049,0.00001908868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002098487,"about_ca_system_score_gemma":0.0004526707,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004328696,"about_ca_topic_score_gemma":0.03842545,"domain_scores_codex":[0.9886551,0.008341318,0.0008487524,0.0007432139,0.0004930763,0.0009185061],"domain_scores_gemma":[0.9933507,0.005612236,0.0002038854,0.0005637595,0.0001438396,0.000125619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00103943,0.001133479,0.9917324,0.000007347659,0.00002676516,0.0004510434,0.00011339,0.0005928316,0.001342162,0.0001528783,0.002255721,0.001152618],"study_design_scores_gemma":[0.001396555,0.0006172769,0.9479479,0.00001244014,0.000005379616,0.00004189425,0.002865979,0.003475971,0.00003721607,0.001477779,0.04195645,0.0001652188],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788495,0.00099463,0.0000384338,0.01465918,0.0001123428,0.0005477158,0.00001717582,0.000004381463,0.004776664],"genre_scores_gemma":[0.9960017,0.002239425,0.0003407102,0.0004450358,0.0001527742,0.0001932437,0.00003591439,0.00001778679,0.000573392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0437845,"threshold_uncertainty_score":0.9999877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08372381712504959,"score_gpt":0.4466139367356664,"score_spread":0.3628901196106168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}