{"id":"W4280536183","doi":"10.2217/nmt-2021-0055","title":"Glutamate Modulation for the Treatment of Levodopa Induced Dyskinesia: A Brief Review of the Drugs Tested in the Clinic","year":2022,"lang":"en","type":"review","venue":"Neurodegenerative Disease Management","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre; Université de Montréal; Montreal Neurological Institute and Hospital","funders":"","keywords":"Dyskinesia; Levodopa; Glutamate receptor; Pharmacology; Medicine; Internal medicine; Disease; Parkinson's disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004156709,0.0009484302,0.001268555,0.001680964,0.0002013222,0.0006883508,0.0008842533,0.000883069,0.003576207],"category_scores_gemma":[0.0004617462,0.0002644851,0.0005668179,0.001494053,0.0002785311,0.0008116385,0.0004479171,0.001784777,0.002506224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003776206,"about_ca_system_score_gemma":0.0006034203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000880751,"about_ca_topic_score_gemma":0.002749911,"domain_scores_codex":[0.9998889,0.00002072836,0.00002047333,0.00002057731,0.00003556628,0.00001375551],"domain_scores_gemma":[0.9998351,0.00008498843,0.00002544159,0.000004919121,0.00003324458,0.00001628352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002075778,0.0001437256,0.00009126635,0.0172574,0.000128682,0.0003202835,0.00004133481,0.0002927849,0.003917329,0.002262734,0.02961181,0.9457251],"study_design_scores_gemma":[0.0000883294,0.000466371,0.0009211581,0.004509519,0.0002740476,0.002285395,0.00004253611,0.0001601162,0.001237097,0.001657975,0.9883212,0.0000361803],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001347695,0.9986474,0.0001087888,0.0001371233,0.0001461293,0.000006893452,0.00002941788,0.000008608215,0.0007808713],"genre_scores_gemma":[0.0006818589,0.9982927,0.0001896422,0.0001868704,0.0001234423,0.000009912037,0.00004091081,0.00000156008,0.0004731231],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003576207,"threshold_uncertainty_score":0.01196367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2033096574134372,"score_gpt":0.4318419586646923,"score_spread":0.2285323012512551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}