{"id":"W4280546958","doi":"10.1038/s41433-022-02108-0","title":"Sensitivity analysis in clinical trials: three criteria for a valid sensitivity analysis","year":2022,"lang":"en","type":"letter","venue":"Eye","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; McMaster University; Impact","funders":"Medical Research Council; National Institute for Health and Care Research","keywords":"Sensitivity (control systems); Medicine; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaresearch","research_integrity"],"category_scores_codex":[0.200225,0.0009555395,0.01242817,0.001750191,0.0002165366,0.0002045272,0.0005092255,0.002353907,0.003815857],"category_scores_gemma":[0.6064276,0.0008786697,0.009362623,0.00428835,0.0003964925,0.00008601323,0.0006078937,0.004903093,0.00002946967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003488122,"about_ca_system_score_gemma":0.0002477885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003458368,"about_ca_topic_score_gemma":0.001459015,"domain_scores_codex":[0.9118049,0.0754687,0.007599816,0.002500334,0.001496229,0.001130033],"domain_scores_gemma":[0.5130447,0.4817008,0.002605421,0.00214077,0.0003140445,0.0001942147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001741538,0.001235591,0.01546026,0.0009629354,0.06071713,0.004321319,0.0001439473,0.0001599426,0.00002516923,0.001911342,0.9007465,0.01257431],"study_design_scores_gemma":[0.004272322,0.0005433719,0.01487272,0.0001209741,0.1571569,0.000007535638,0.00004844539,0.0518962,0.00002732134,0.6820849,0.08658523,0.002384077],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.002865418,0.00003716339,0.8654903,0.1148136,0.002992594,0.002936856,0.01026264,0.0002352716,0.0003662056],"genre_scores_gemma":[0.00354185,0.00004054728,0.8495933,0.1307812,0.01297427,0.0006771322,0.001066388,0.0002754903,0.00104979],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.8141613,"threshold_uncertainty_score":0.9993664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.7555676095515504,"score_gpt":0.6531789994994113,"score_spread":0.1023886100521392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}