{"id":"W4280548780","doi":"10.1097/j.pain.0000000000002694","title":"Altered serum bile acid profile in fibromyalgia is associated with specific gut microbiome changes and symptom severity","year":2022,"lang":"en","type":"article","venue":"Pain","topic":"Fibromyalgia and Chronic Fatigue Syndrome Research","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University and Génome Québec Innovation Centre; Université de Montréal; McGill University Health Centre","funders":"","keywords":"Fibromyalgia; Microbiome; Bile acid; Gut flora; Internal medicine; Physiology; Biology; Medicine; Endocrinology; Gastroenterology; Immunology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001717784,0.0001948102,0.0003630358,0.0002488616,0.0001687091,0.00003021655,0.0001356584,0.0000818734,0.003774839],"category_scores_gemma":[0.00008199464,0.000172537,0.00004269097,0.0006994781,0.0001154328,0.00005060732,0.0001826543,0.000450683,0.00002688316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004480832,"about_ca_system_score_gemma":0.0001897706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008957148,"about_ca_topic_score_gemma":0.00001332971,"domain_scores_codex":[0.9977742,0.0006036217,0.0001934513,0.0004478804,0.0004255495,0.0005553178],"domain_scores_gemma":[0.9992518,0.0001674161,0.0000691305,0.0003195649,0.00004644743,0.0001456047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00131347,0.001806902,0.2328355,0.009379228,0.0007505183,0.001529271,0.01143806,0.00000691189,0.565841,0.00005805399,0.1583565,0.01668464],"study_design_scores_gemma":[0.01982848,0.0103867,0.8733087,0.005092002,0.0001419722,0.001408535,0.006695069,0.01013477,0.04496142,0.0002547199,0.02571181,0.0020758],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937099,0.001368822,0.00001519476,0.003467329,0.00005989876,0.0007900087,0.0002491472,0.00007513974,0.0002645794],"genre_scores_gemma":[0.9955862,0.00006483765,0.000235025,0.00006387744,0.00001776475,0.0001626347,0.0002741209,0.00004218424,0.003553351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6404732,"threshold_uncertainty_score":0.9971358,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0172473585555652,"score_gpt":0.2474244195850721,"score_spread":0.2301770610295069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}