{"id":"W4280567845","doi":"10.21203/rs.3.rs-1647065/v1","title":"Single-cell transcriptomics reveals diversity during heart valve epithelial-to-mesenchymal transitions","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; University of British Columbia","funders":"British Columbia Knowledge Development Fund; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Mesenchymal stem cell; Diversity (politics); Transcriptome; Cell; Cell biology; Biology; Gene; Gene expression; Genetics; Political science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001819078,0.0001041577,0.0002593515,0.0003421121,0.0001658249,0.0004937097,0.000113431,0.0002437469,0.0007112877],"category_scores_gemma":[0.0001981842,0.0001460928,0.0001537996,0.000240728,0.0002093091,0.0002338523,0.0002196246,0.0002696447,0.0003813868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001406443,"about_ca_system_score_gemma":0.0001065472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003257379,"about_ca_topic_score_gemma":0.0009053326,"domain_scores_codex":[0.9998932,0.000006536115,0.000005324476,0.0000407123,0.0000346305,0.00001950765],"domain_scores_gemma":[0.9998763,0.00004110992,0.00002626873,0.00001508735,0.00002213555,0.00001918596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00002813562,0.000002925944,0.001814849,0.00002415594,0.000004328114,0.00002548502,0.00002550967,0.0001205613,0.9961141,0.00008153292,0.00005237016,0.001706102],"study_design_scores_gemma":[0.000009902684,0.000111081,0.2340948,0.00002422959,0.00003957271,0.0004620102,0.0002746741,0.007850225,0.7501022,0.0008045107,0.006203028,0.00002362519],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9732065,0.001465599,0.01894772,0.00009340588,0.00003232374,0.00001803991,0.004276452,0.0002215968,0.00173843],"genre_scores_gemma":[0.978713,0.00108278,0.01324164,0.0001264285,0.00002542929,0.00004619807,0.003899323,0.0001435272,0.002721759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007112877,"threshold_uncertainty_score":0.002379537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04199787833869947,"score_gpt":0.3320914955644922,"score_spread":0.2900936172257927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}