{"id":"W4280573405","doi":"10.1016/j.pnpbp.2022.110576","title":"Age-associated alterations in immune function and inflammation","year":2022,"lang":"en","type":"review","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":107,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Immunosenescence; Immune system; Immunology; Inflammation; Biology; Antigen; T cell; Population; Context (archaeology); Innate immune system; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000547877,0.0005211084,0.0009777504,0.0006665477,0.0003536605,0.0001025969,0.0003150821,0.0004583136,0.0003184641],"category_scores_gemma":[0.0002978964,0.0004443931,0.0001511117,0.0009840179,0.0002860791,0.0001879644,0.00022942,0.001497977,0.00001518589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004821726,"about_ca_system_score_gemma":0.00008205377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":9.616135e-7,"about_ca_topic_score_gemma":0.0000124101,"domain_scores_codex":[0.9945977,0.002300286,0.001191039,0.001250499,0.0002050031,0.0004554792],"domain_scores_gemma":[0.9982918,0.0007928053,0.0005603308,0.0002246704,0.0000129443,0.0001174298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007985616,0.001255608,0.007973321,0.001751031,0.00004062602,0.0003786991,0.0001027388,0.00001406872,0.001352521,0.01842571,0.000311658,0.9675955],"study_design_scores_gemma":[0.008570315,0.002156114,0.03246549,0.001051592,0.0003260855,0.0004527495,0.00003458293,0.0005955142,0.00006907203,0.01095522,0.9413224,0.002000838],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1000103,0.8905683,0.000009886079,0.001041905,0.005129687,0.002673381,0.00005478868,0.0002536534,0.000258106],"genre_scores_gemma":[0.01547113,0.981724,0.00004925429,0.001359328,0.0001863567,0.001019472,0.0001001869,0.00004214698,0.000048122],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9655946,"threshold_uncertainty_score":0.9998008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07710210710447324,"score_gpt":0.3586145598151527,"score_spread":0.2815124527106795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}