{"id":"W4280574452","doi":"10.1101/2022.05.10.491275","title":"HIV rapidly targets a diverse pool of CD4+ T cells to establish productive and latent infections","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Université de Montréal","funders":"ViiV Healthcare; Gilead Sciences","keywords":"Biology; Lymph; Phenotype; Immunology; Virology; Lymphatic system; Human immunodeficiency virus (HIV); Gene; Genetics; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002525674,0.0001462178,0.000203034,0.0002817999,0.0002662115,0.0006364862,0.0001672698,0.0002236647,0.004301229],"category_scores_gemma":[0.0001846331,0.0001471945,0.0001122417,0.0001431953,0.0001847277,0.000362275,0.0004371925,0.0005527894,0.001417688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002163216,"about_ca_system_score_gemma":0.0002411548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000180778,"about_ca_topic_score_gemma":0.0001871953,"domain_scores_codex":[0.9998472,0.00002428942,0.000008395737,0.00002922814,0.00004130242,0.00004952845],"domain_scores_gemma":[0.999887,0.00002767829,0.00001924202,0.00001685897,0.00001163955,0.00003759185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000134879,0.00003453135,0.003677318,0.00004092171,0.000004064295,0.0001178203,0.00004581616,0.0001048073,0.9906698,0.0003961061,0.0002026895,0.004571255],"study_design_scores_gemma":[0.0001154955,0.001192646,0.08244151,0.00006609783,0.00004789753,0.002304241,0.0003776593,0.003681703,0.8914708,0.002533767,0.01574557,0.0000225785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917337,0.001228343,0.003569801,0.00009057228,0.00001957937,0.00002856353,0.0003293836,0.0001063428,0.002893754],"genre_scores_gemma":[0.9935033,0.0003349925,0.001918682,0.00007665725,0.00002782387,0.00003315565,0.0005184696,0.00002944712,0.003557564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004301229,"threshold_uncertainty_score":0.01438904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01175795494315169,"score_gpt":0.2242599912002586,"score_spread":0.2125020362571069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}