{"id":"W4280578378","doi":"10.3389/fbioe.2022.890479","title":"Bioengineered Probiotics: Synthetic Biology Can Provide Live Cell Therapeutics for the Treatment of Foodborne Diseases","year":2022,"lang":"en","type":"review","venue":"Frontiers in Bioengineering and Biotechnology","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Social Sciences and Humanities Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Department of Science and Technology, Republic of the Philippines","keywords":"Biology; Antimicrobial; Antibiotics; Clostridium difficile; Microbiology; Antibiotic resistance; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003108792,0.0007185737,0.000698999,0.001596101,0.0001923278,0.0009010178,0.0004409441,0.0008826312,0.003422525],"category_scores_gemma":[0.0003198644,0.0002071727,0.0003902994,0.001554567,0.000300189,0.001152519,0.0006176052,0.001482743,0.002032328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003842943,"about_ca_system_score_gemma":0.0005638995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005518029,"about_ca_topic_score_gemma":0.001004654,"domain_scores_codex":[0.9998733,0.00001896137,0.000009582459,0.00001948685,0.00006093064,0.00001786526],"domain_scores_gemma":[0.9999027,0.00004192221,0.00001428845,0.000004123471,0.00002514453,0.00001177103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000071769,0.0001091845,0.0001173958,0.01657409,0.00006394654,0.0001977631,0.00009123216,0.0005690578,0.01645433,0.01283185,0.02267098,0.9302483],"study_design_scores_gemma":[0.000006284583,0.00008021927,0.0002695354,0.001524747,0.00002970384,0.00031995,0.00004169456,0.00007465267,0.001535509,0.001791679,0.9943156,0.00001041725],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003438105,0.9958418,0.000385676,0.0002703751,0.000279353,0.00000660964,0.00002645627,0.00001164954,0.002834213],"genre_scores_gemma":[0.001749578,0.9959567,0.0004018903,0.0001730301,0.0001064932,0.000008401968,0.00004211016,0.000003125784,0.001558574],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003422525,"threshold_uncertainty_score":0.01144952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02744463825493479,"score_gpt":0.2358314120780411,"score_spread":0.2083867738231063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}