{"id":"W4280578572","doi":"10.1093/molbev/msac101","title":"Mutation Load in Sunflower Inversions Is Negatively Correlated with Inversion Heterozygosity","year":2022,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; China Scholarship Council","keywords":"Biology; Genetics; Overdominance; Recombination; Chromosomal inversion; Loss of heterozygosity; Ectopic recombination; Evolutionary biology; Balancing selection; Genetic load; Transposable element; Local adaptation; Allele; Genome; Inbreeding; Gene; Population; Genetic recombination; Chromosome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009498085,0.00007113371,0.00007371567,0.00001847932,0.000329311,0.000006229777,0.00005765411,0.00006318003,0.0002187849],"category_scores_gemma":[0.00001314194,0.00003442828,0.00002308375,0.0003161262,0.00005793408,0.00003796513,0.00008224038,0.000120561,0.000006724608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008823456,"about_ca_system_score_gemma":0.00001599701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006671943,"about_ca_topic_score_gemma":0.0006269354,"domain_scores_codex":[0.9993518,0.0001385235,0.00008882773,0.0002119616,0.00008124572,0.0001276659],"domain_scores_gemma":[0.9998346,0.00002664749,0.00004246073,0.00002814383,0.00003234308,0.00003578278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002785035,0.0002069448,0.2996205,0.000003560671,0.00003114151,0.00003183715,0.0007407122,0.0006246468,0.6930258,0.00205013,0.0003082703,0.003077929],"study_design_scores_gemma":[0.001056187,0.001400419,0.9749531,0.00001295328,0.00002950077,0.00007674306,0.0006926595,0.005834446,0.003747776,0.008959213,0.002943151,0.0002938775],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975528,0.0001270819,0.0001733407,0.001762721,0.00005649044,0.0001345775,0.00003508534,0.00001847668,0.0001394718],"genre_scores_gemma":[0.9992446,0.000006685447,0.00007045138,0.000474783,0.000009148094,0.00001812263,0.0001290673,4.857743e-7,0.00004665679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6892781,"threshold_uncertainty_score":0.2532827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006450482354443444,"score_gpt":0.2006175257934027,"score_spread":0.1941670434389593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}