{"id":"W4280578572","doi":"10.1093/molbev/msac101","title":"Mutation Load in Sunflower Inversions Is Negatively Correlated with Inversion Heterozygosity","year":2022,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; China Scholarship Council","keywords":"Biology; Genetics; Overdominance; Recombination; Chromosomal inversion; Loss of heterozygosity; Ectopic recombination; Evolutionary biology; Balancing selection; Genetic load; Transposable element; Local adaptation; Allele; Genome; Inbreeding; Gene; Population; Genetic recombination; Chromosome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005600236,0.0002517781,0.0004316673,0.001801446,0.0003151117,0.0004547893,0.0002016822,0.0003194349,0.0009239761],"category_scores_gemma":[0.001676278,0.0001892735,0.0002308928,0.0006220452,0.0003818581,0.0003198464,0.0004296586,0.0003959589,0.0001075346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002468939,"about_ca_system_score_gemma":0.0001335649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009424557,"about_ca_topic_score_gemma":0.001489436,"domain_scores_codex":[0.9995545,0.00005294607,0.00004118795,0.0001773127,0.0001146409,0.00005945087],"domain_scores_gemma":[0.9979261,0.0007017085,0.0008865636,0.0001203235,0.0001278319,0.0002374398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003490481,0.00006749597,0.7303653,0.00002971875,0.0001553353,0.0001799748,0.0002326046,0.0003825519,0.2617847,0.0001037342,0.00003863736,0.006310846],"study_design_scores_gemma":[0.000004737958,0.00007709002,0.9956185,0.000002369364,0.00002507934,0.0002678803,0.00003763791,0.0006968012,0.003112398,0.00008177792,0.0000658606,0.000009737757],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996358,0.00004675775,0.0001887607,0.000003714529,6.608404e-7,0.000001062222,0.00004018967,0.000009090747,0.00007387501],"genre_scores_gemma":[0.9995075,0.00002000758,0.0002004466,0.000006100512,0.000003027741,0.00000244871,0.0001489522,0.000005921227,0.0001056794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001801446,"threshold_uncertainty_score":0.003090978,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006450482354443444,"score_gpt":0.2006175257934027,"score_spread":0.1941670434389593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}