{"id":"W4280585986","doi":"10.1016/j.chom.2022.04.005","title":"Supplementation with a probiotic mixture accelerates gut microbiome maturation and reduces intestinal inflammation in extremely preterm infants","year":2022,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":186,"is_retracted":false,"has_abstract":false,"ca_institutions":"Calgary Laboratory Services; Health Sciences Centre; Lallemand (Canada); Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Cumming School of Medicine, University of Calgary; Mitacs; Alberta Children's Hospital Research Institute; Science Foundation Ireland","keywords":"Microbiome; Bifidobacterium; Biology; Necrotizing enterocolitis; Probiotic; Immune system; Bifidobacterium longum; Immunology; Gut microbiome; Immunity; Sepsis; Lactobacillus; Physiology; Bioinformatics; Internal medicine; Medicine; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001705229,0.0001919218,0.0001412254,0.0001279274,0.00019427,0.00007477203,0.0001339846,0.00007868428,0.00007631682],"category_scores_gemma":[0.000007555814,0.0001865577,0.00002442089,0.0001868546,0.00005814909,0.00002035962,0.0001528055,0.0001812428,0.000003422471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006875757,"about_ca_system_score_gemma":0.0001306142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005795785,"about_ca_topic_score_gemma":0.0001839052,"domain_scores_codex":[0.9988575,0.0001013128,0.0002862089,0.0004105874,0.00007275255,0.0002716694],"domain_scores_gemma":[0.9995431,0.000008609737,0.0001742227,0.0001640459,0.00006172925,0.00004834789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004203283,0.00006289352,0.004846127,0.0001088165,0.000008999705,0.000005143138,0.0007953303,0.00002638667,0.9922308,0.000002850636,0.0009812274,0.000511058],"study_design_scores_gemma":[0.001359653,0.0005609385,0.02484011,0.00005099657,0.00001726955,0.0001841756,0.0005106318,0.00002973122,0.9666115,0.000006098026,0.005556069,0.0002728462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980354,0.0006562757,0.00004905395,0.0002957935,0.00007663877,0.0006863388,0.00006955933,0.00001333767,0.0001176291],"genre_scores_gemma":[0.9956579,0.0001004042,0.001807941,0.000166768,0.00006786325,0.00006265337,0.001673848,0.00002578553,0.0004368531],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02561936,"threshold_uncertainty_score":0.7607602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006627611520872284,"score_gpt":0.2294141823214441,"score_spread":0.2227865708005718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}