{"id":"W4280585986","doi":"10.1016/j.chom.2022.04.005","title":"Supplementation with a probiotic mixture accelerates gut microbiome maturation and reduces intestinal inflammation in extremely preterm infants","year":2022,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":186,"is_retracted":false,"has_abstract":false,"ca_institutions":"Calgary Laboratory Services; Health Sciences Centre; Lallemand (Canada); Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Cumming School of Medicine, University of Calgary; Mitacs; Alberta Children's Hospital Research Institute; Science Foundation Ireland","keywords":"Microbiome; Bifidobacterium; Biology; Necrotizing enterocolitis; Probiotic; Immune system; Bifidobacterium longum; Immunology; Gut microbiome; Immunity; Sepsis; Lactobacillus; Physiology; Bioinformatics; Internal medicine; Medicine; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000167707,0.0003174471,0.0006732659,0.0002469231,0.0001755726,0.0002848665,0.0002533179,0.0004088474,0.001313572],"category_scores_gemma":[0.0005006577,0.0001582303,0.000242679,0.0001229011,0.0001599127,0.0001990552,0.0004206069,0.0006718983,0.0001665833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000122461,"about_ca_system_score_gemma":0.0002314802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005688076,"about_ca_topic_score_gemma":0.0008487554,"domain_scores_codex":[0.9998637,0.00005066564,0.00001118255,0.00002487469,0.00002529961,0.00002421489],"domain_scores_gemma":[0.9998705,0.00001977348,0.00003218803,0.000009217964,0.0000119891,0.00005624866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0350768,0.002382814,0.004222719,0.0005623149,0.0002252386,0.0002680147,0.0002055352,0.0001669543,0.886407,0.0001398313,0.0007433147,0.06959949],"study_design_scores_gemma":[0.003235412,0.1084701,0.1716131,0.000684534,0.002037404,0.001999411,0.001211868,0.004058906,0.6865658,0.0007087254,0.01929323,0.0001216047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963297,0.002349121,0.0005970715,0.0001308088,0.00006575208,0.00002097976,0.0001042727,0.00005744002,0.0003448371],"genre_scores_gemma":[0.9950487,0.001386568,0.001792556,0.0001212407,0.00002869347,0.00005596567,0.0002031274,0.00001977093,0.00134339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001313572,"threshold_uncertainty_score":0.004394293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006627611520872284,"score_gpt":0.2294141823214441,"score_spread":0.2227865708005718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}