{"id":"W4280588204","doi":"10.15252/msb.202110823","title":"Human phospho‐signaling networks of SARS‐CoV‐2 infection are rewired by population genetic variants","year":2022,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Genetics; Population; Virology; Computational biology; Demography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003629509,0.0001904014,0.0004341007,0.0001615403,0.000313846,0.00001023856,0.0002010087,0.0002809968,0.0001313587],"category_scores_gemma":[0.00003749734,0.0001949151,0.0001251363,0.000182518,0.00008443266,0.00002384126,0.0001511539,0.0002949267,0.00001974692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009798721,"about_ca_system_score_gemma":0.00001986688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003052138,"about_ca_topic_score_gemma":0.00001381071,"domain_scores_codex":[0.9970837,0.001644392,0.0005622455,0.0003393364,0.00003757564,0.0003327452],"domain_scores_gemma":[0.9991196,0.00003602087,0.0004439538,0.0003255013,0.00006344081,0.00001152691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001373658,0.0001042599,0.00845994,0.00002017894,0.000202629,0.000007689095,0.00005438282,0.0008492397,0.9878582,0.0004731497,0.001450151,0.0003828288],"study_design_scores_gemma":[0.003915455,0.002660915,0.05407275,0.0001407633,0.0001879385,0.0006669108,0.000310956,0.0009467482,0.9063796,0.0001475722,0.02969484,0.0008755281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9796208,0.01082875,0.007125276,0.00002224471,0.001826193,0.0003519937,0.00005111003,0.00006253727,0.0001111221],"genre_scores_gemma":[0.9988133,0.00001974092,0.00001088506,0.0001073074,0.00001954012,0.00008994874,0.0005012965,0.00002747026,0.000410551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08147857,"threshold_uncertainty_score":0.7948408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01328300391954019,"score_gpt":0.251409328277322,"score_spread":0.2381263243577818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}