{"id":"W4280589239","doi":"10.1097/ccm.0000000000005591","title":"A Randomized Double-Blinded Placebo Controlled Trial of Clazakizumab for the Treatment of COVID-19 Pneumonia With Hyperinflammation*","year":2022,"lang":"en","type":"article","venue":"Critical Care Medicine","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"ViTRAK Systems (Canada)","funders":"","keywords":"Medicine; Placebo; Odds ratio; Randomized controlled trial; Internal medicine; Clinical endpoint; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004640548,0.002599611,0.004566409,0.0007527618,0.0009790321,0.001566631,0.001353779,0.003445728,0.007195879],"category_scores_gemma":[0.005300796,0.001182798,0.002226279,0.0005271374,0.002057422,0.001457494,0.0005832679,0.003142772,0.001129858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001022794,"about_ca_system_score_gemma":0.002858205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009208237,"about_ca_topic_score_gemma":0.001931872,"domain_scores_codex":[0.9975286,0.00149486,0.0002419759,0.00034274,0.0001743408,0.0002174242],"domain_scores_gemma":[0.9972888,0.0008229947,0.0007365691,0.0002327184,0.0002439191,0.0006748714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9892341,0.004503049,0.0001502386,0.0004254421,0.0004040794,0.00001579671,0.00001655056,0.0000781406,0.0008346443,0.0000517453,0.0002555128,0.004030593],"study_design_scores_gemma":[0.9856984,0.0137691,0.0001351428,0.00001262218,0.0001010609,0.000004655267,0.000002768928,0.00007070082,0.00006357078,0.00002844556,0.0001101292,0.000003432595],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9316217,0.01172252,0.002786497,0.002183804,0.003457765,0.04172571,0.002002691,0.0003093953,0.004189853],"genre_scores_gemma":[0.9359729,0.00432282,0.006385885,0.003649652,0.001501538,0.0434045,0.001249452,0.00004545984,0.003467791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007195879,"threshold_uncertainty_score":0.02454185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1045278135735441,"score_gpt":0.4654915269786671,"score_spread":0.3609637134051231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}