{"id":"W4280591169","doi":"10.1007/s43440-022-00370-3","title":"Recent progress in biologically active indole hybrids: a mini review","year":2022,"lang":"en","type":"review","venue":"Pharmacological Reports","topic":"Synthesis of Indole Derivatives","field":"Chemistry","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Indole test; Isatin; Chalcone; Biological activity; Antifungal; Chemistry; Pyrimidine; Drug discovery; Combinatorial chemistry; Biochemistry; Biology; Organic chemistry; Microbiology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001497459,0.001068478,0.004093514,0.000193574,0.0001441273,0.00004484633,0.001020359,0.0005432838,0.05389476],"category_scores_gemma":[0.00391657,0.0007623222,0.001013863,0.0008810257,0.0003445928,0.0001125513,0.001112623,0.002199842,0.00007660403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001013279,"about_ca_system_score_gemma":0.0006528221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002916515,"about_ca_topic_score_gemma":6.377495e-7,"domain_scores_codex":[0.9927807,0.000871857,0.00269662,0.001898992,0.0008114129,0.0009404231],"domain_scores_gemma":[0.994252,0.001934307,0.002660434,0.0007308209,0.0001029305,0.0003195057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000365431,0.0008327449,0.00004754397,0.01662211,0.0003186235,0.01036761,0.00001191985,8.391137e-8,0.00001643536,0.000002331292,0.004070668,0.9676734],"study_design_scores_gemma":[0.0001835301,0.00005968221,0.00001208034,0.02015119,0.0007727979,0.001319582,0.0000182248,3.750807e-7,0.0002530495,0.00004315596,0.9763372,0.0008491583],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001782159,0.9790816,1.741252e-7,0.000222127,0.0003645686,0.001815402,0.00008460729,0.0002767366,0.0179766],"genre_scores_gemma":[0.0000311581,0.9904006,0.0001213831,0.0006423674,0.000254322,0.007622628,0.0004698021,0.00009141463,0.0003663581],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9722665,"threshold_uncertainty_score":0.9994828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1257433519135173,"score_gpt":0.4120789794125042,"score_spread":0.2863356274989869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}