{"id":"W4280591169","doi":"10.1007/s43440-022-00370-3","title":"Recent progress in biologically active indole hybrids: a mini review","year":2022,"lang":"en","type":"review","venue":"Pharmacological Reports","topic":"Synthesis of Indole Derivatives","field":"Chemistry","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Indole test; Isatin; Chalcone; Biological activity; Antifungal; Chemistry; Pyrimidine; Drug discovery; Combinatorial chemistry; Biochemistry; Biology; Organic chemistry; Microbiology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003546904,0.0008050355,0.0009490285,0.00123895,0.0002128362,0.000894966,0.0006161691,0.0006623536,0.004485148],"category_scores_gemma":[0.0003784679,0.0003410576,0.0003922917,0.001274575,0.0002750826,0.001074175,0.0005969338,0.001406729,0.001823754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003843247,"about_ca_system_score_gemma":0.0006381925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000464275,"about_ca_topic_score_gemma":0.001072039,"domain_scores_codex":[0.9999149,0.00001130237,0.00001000897,0.00002127581,0.00002501661,0.00001745117],"domain_scores_gemma":[0.9998734,0.00006177837,0.00002262671,0.000004086431,0.00002212612,0.00001592377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002106103,0.0001794218,0.0001653501,0.03091675,0.0001060842,0.0003527032,0.00008073013,0.0007861181,0.0250414,0.004187785,0.02592127,0.9120519],"study_design_scores_gemma":[0.00002859941,0.0002578593,0.0004961512,0.00164505,0.0001830033,0.0006967013,0.00005227072,0.0001803757,0.005544328,0.001242546,0.9896412,0.00003173979],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005934494,0.9965131,0.0004755124,0.0001898204,0.0003414933,0.00001093107,0.00005413211,0.00002288945,0.001798646],"genre_scores_gemma":[0.001862403,0.9961299,0.0004668878,0.0001918776,0.0002012496,0.00001101731,0.00006982049,0.00000378898,0.001063011],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004485148,"threshold_uncertainty_score":0.01500434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1257433519135173,"score_gpt":0.4120789794125042,"score_spread":0.2863356274989869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}