{"id":"W4280595918","doi":"10.1111/ctr.14699","title":"Combining donor derived cell free DNA and gene expression profiling for non‐invasive surveillance after heart transplantation","year":2022,"lang":"en","type":"article","venue":"Clinical Transplantation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ted Rogers Centre for Heart Research; University Health Network","funders":"","keywords":"Medicine; Cohort; Transplantation; Internal medicine; Heart transplantation; Cell-free fetal DNA; Retrospective cohort study; Gene expression profiling; Oncology; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00116704,0.0002550545,0.0005656515,0.0001225442,0.0003672733,0.00003114543,0.0001186336,0.0001482689,0.00006245248],"category_scores_gemma":[0.00007726259,0.0002438792,0.0002513771,0.000154914,0.00009806902,0.0001641551,0.00001571133,0.0003700596,0.00000347792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003299384,"about_ca_system_score_gemma":0.0001251718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001139824,"about_ca_topic_score_gemma":0.00002619001,"domain_scores_codex":[0.9974574,0.0003891604,0.0008629986,0.0006204351,0.0003441451,0.0003258549],"domain_scores_gemma":[0.997179,0.002061056,0.0001886281,0.0002769936,0.0001015327,0.0001927795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01311261,0.0004002673,0.4474953,0.003044902,0.00009068389,0.0001906069,0.003699944,0.0001581849,0.5304492,0.00004986615,0.00007010621,0.001238321],"study_design_scores_gemma":[0.01654074,0.001317416,0.5381684,0.0002414861,0.0005485001,0.0002631469,0.0005025609,0.0004806692,0.4409736,0.00038682,0.0001392196,0.0004374367],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9319797,0.0001898852,0.06435163,0.0005018623,0.0006136419,0.00138289,0.0007691784,0.00009021256,0.0001210701],"genre_scores_gemma":[0.8985114,0.001275263,0.0971478,0.0008896414,0.0001993731,0.0005035051,0.001359852,0.00004848905,0.00006466008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09067309,"threshold_uncertainty_score":0.9945105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.047666992535796,"score_gpt":0.3523856940334403,"score_spread":0.3047187014976444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}