{"id":"W4280595918","doi":"10.1111/ctr.14699","title":"Combining donor derived cell free DNA and gene expression profiling for non‐invasive surveillance after heart transplantation","year":2022,"lang":"en","type":"article","venue":"Clinical Transplantation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ted Rogers Centre for Heart Research; University Health Network","funders":"","keywords":"Medicine; Cohort; Transplantation; Internal medicine; Heart transplantation; Cell-free fetal DNA; Retrospective cohort study; Gene expression profiling; Oncology; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002300357,0.0002383114,0.0004559194,0.001071524,0.0001491222,0.001041034,0.0003125964,0.0002646307,0.0006842473],"category_scores_gemma":[0.002843899,0.0001122192,0.0003006238,0.0006982413,0.0004676705,0.000575775,0.00054607,0.0003758656,0.0001563314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003042662,"about_ca_system_score_gemma":0.0003817482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002033481,"about_ca_topic_score_gemma":0.0005400605,"domain_scores_codex":[0.9987113,0.0004701362,0.0001111935,0.0002493657,0.0003417907,0.0001161656],"domain_scores_gemma":[0.9978205,0.0007661798,0.0009030543,0.000140925,0.0001948994,0.0001744082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008723615,0.0001255558,0.9485571,0.0001024142,0.0001009016,0.0001929309,0.00009482123,0.0002799591,0.007815753,0.00006444262,0.0001794562,0.04161432],"study_design_scores_gemma":[0.00007906243,0.002452434,0.9729643,0.000108409,0.0002290015,0.002968191,0.0004006389,0.001987727,0.01677174,0.0003021632,0.001705476,0.00003093629],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949229,0.001729171,0.002105294,0.0001014737,0.00002434478,0.00005022021,0.0002540702,0.00001807791,0.0007944624],"genre_scores_gemma":[0.9973541,0.0004485335,0.00169859,0.00006448164,0.00003623065,0.00002716987,0.0002266812,0.000004348597,0.0001398728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002300357,"threshold_uncertainty_score":0.01216555,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.047666992535796,"score_gpt":0.3523856940334403,"score_spread":0.3047187014976444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}