{"id":"W4280598233","doi":"10.1016/j.crstbi.2022.05.001","title":"Multifaceted membrane binding head of the SARS-CoV-2 spike protein","year":2022,"lang":"en","type":"article","venue":"Current Research in Structural Biology","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Endocytic cycle; Lipid bilayer fusion; Membrane; Biophysics; Docking (animal); Cell biology; Chemistry; Membrane protein; Ectodomain; Biochemistry; Biology; Receptor; Endocytosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000553748,0.0002672983,0.0001978704,0.0001726157,0.0002943164,0.0003337439,0.0001809636,0.0002973846,0.002000318],"category_scores_gemma":[0.00006955705,0.0001619981,0.0002496471,0.0001498976,0.000266712,0.0003908355,0.0003679547,0.0004216155,0.0003883235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003459151,"about_ca_system_score_gemma":0.0003064323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001130213,"about_ca_topic_score_gemma":0.00141439,"domain_scores_codex":[0.9999508,0.000005288346,0.000001612058,0.00001195645,0.00001809691,0.00001222354],"domain_scores_gemma":[0.9999671,0.000003687839,0.00001051379,0.000002590664,0.000005154474,0.00001095485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001741409,0.00001982155,0.001194369,0.00005547954,0.000009943113,0.0002212456,0.00004930718,0.001336157,0.9912084,0.001746942,0.0001825265,0.00380163],"study_design_scores_gemma":[0.00006729372,0.0005161377,0.0588082,0.00004100364,0.00007242235,0.00227885,0.0004994551,0.05337187,0.8615146,0.005554345,0.01719873,0.00007722234],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842014,0.001010454,0.0110712,0.0002548144,0.00002447932,0.00001724261,0.0002536511,0.0001750085,0.002991744],"genre_scores_gemma":[0.9914532,0.0003915529,0.005946943,0.0000808358,0.000005708612,0.000006341883,0.0002667283,0.00001407744,0.001834627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002000318,"threshold_uncertainty_score":0.006691754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1950039973371108,"score_gpt":0.4814106504771291,"score_spread":0.2864066531400183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}