{"id":"W4280616627","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5756","title":"A Randomized, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Inhaled Ribavirin Administered Via Air-Jet Nebulizer in Healthy Volunteers","year":2022,"lang":"en","type":"article","venue":"","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Bausch Health (Canada)","funders":"","keywords":"Nebulizer; Tolerability; Pharmacokinetics; Medicine; Ribavirin; Placebo; Anesthesia; Pharmacology; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002657729,0.001871401,0.004466915,0.0005130094,0.0009196772,0.001056309,0.001200779,0.003414862,0.005493688],"category_scores_gemma":[0.002735924,0.001214829,0.001792778,0.0004793235,0.002532544,0.00141991,0.0005355692,0.002804707,0.0008478141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005437855,"about_ca_system_score_gemma":0.00124264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009468772,"about_ca_topic_score_gemma":0.001595926,"domain_scores_codex":[0.9986468,0.0006324885,0.0001038234,0.0003329219,0.0001114702,0.0001726101],"domain_scores_gemma":[0.9982333,0.0006278757,0.0003190072,0.0002222514,0.0001722,0.000425337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9812809,0.009273279,0.0003992018,0.0002639506,0.0004135112,0.00003434228,0.00003611607,0.00006461051,0.004029212,0.0000414051,0.0001454639,0.004018039],"study_design_scores_gemma":[0.8677636,0.1293855,0.001495743,0.0000127205,0.0004025239,0.00002183712,0.00001688266,0.0001490155,0.000458629,0.0000445048,0.0002350972,0.00001383936],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894964,0.002586468,0.001073101,0.0003357231,0.0006260205,0.004420332,0.0005017355,0.000100692,0.000859597],"genre_scores_gemma":[0.9857502,0.001682814,0.002810998,0.001269738,0.000895771,0.004391159,0.0006388175,0.00003335237,0.002527225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005493688,"threshold_uncertainty_score":0.01837826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02527268178769574,"score_gpt":0.3325588252524757,"score_spread":0.3072861434647799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}