{"id":"W4280617428","doi":"10.1016/j.bbamcr.2022.119284","title":"Autophagy regulates transforming growth factor β signaling and receptor trafficking","year":2022,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cell biology; Autophagy; Signal transduction; Small interfering RNA; Transforming growth factor; Biology; Cell migration; Phosphorylation; Cell; Endosome; Chemistry; Cell culture; Intracellular; Transfection; Biochemistry; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002273798,0.0002967115,0.0002925564,0.0005556793,0.0005424059,0.001364091,0.0002652935,0.0004549836,0.001683978],"category_scores_gemma":[0.0001970272,0.0002358908,0.000467179,0.0002695974,0.0003982767,0.000954446,0.000447411,0.0008319745,0.001212999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009175119,"about_ca_system_score_gemma":0.0005013064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007173513,"about_ca_topic_score_gemma":0.0009241271,"domain_scores_codex":[0.9997612,0.00002648009,0.00001635733,0.0000459348,0.00005113179,0.00009894335],"domain_scores_gemma":[0.9998734,0.0000138985,0.00003363232,0.00001246452,0.00002548542,0.0000410824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001037771,0.00005302048,0.001167478,0.00006404871,0.00001812958,0.0002765721,0.00007018333,0.0001104483,0.9882753,0.003353892,0.000629176,0.004944008],"study_design_scores_gemma":[0.00008895791,0.0002123099,0.02336285,0.00002952217,0.00004907506,0.001068728,0.0003552312,0.002377553,0.9526569,0.002239172,0.01753417,0.00002556979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9742591,0.01212385,0.003317863,0.0009878932,0.0001716652,0.0000201525,0.0006253992,0.0002218248,0.00827227],"genre_scores_gemma":[0.9899402,0.003260946,0.001194241,0.000151238,0.00003470734,0.000017538,0.0006651917,0.00004950666,0.004686465],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001683978,"threshold_uncertainty_score":0.006657004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03018788479289068,"score_gpt":0.3163226968028749,"score_spread":0.2861348120099842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}